Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL3
 37.0 79
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL3
 47.5 84
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL3
 44.5 70
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
IL3
 41.0 75
N2586 IL-17A 100
ng/mL
 1
IL3
 59.0 38
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
IL3
 44.5 36
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL3
 39.0 39
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL3
 51.0 52
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL3
 37.5 46
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
IL3
 47.0 58
RA2159 1
IL3
 48.0 55
RA2159 PD184352 0.1
uM
 1
IL3
 96.0 64
RA2159 Lestaurtinib 0.3
uM
 1
IL3
 47.0 69
RA2159 Ruxolitinib 0.3
uM
 1
IL3
 43.0 85
RA2159 Tofacitinib 0.3
uM
 1
IL3
 43.0 78
RA2159 IKK16 2.0
uM
 1
IL3
 46.0 69
RA2159 JNK-IN-8 3.0
uM
 1
IL3
 41.5 64
N2586 1
IL3
 49.0 53
N2586 PD184352 0.1
uM
 1
IL3
 50.0 62
N2586 Lestaurtinib 0.3
uM
 1
IL3
 37.5 54
N2586 Ruxolitinib 0.3
uM
 1
IL3
 41.0 73
N2586 Tofacitinib 0.3
uM
 1
IL3
 48.0 63
N2586 IKK16 2.0
uM
 1
IL3
 44.0 61
N2586 JNK-IN-8 3.0
uM
 1
IL3
 48.5 46
RA2159 EGF 100
ng/mL
 1
IL3
 45.5 72