Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
b-NGF
 69.0 53
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
b-NGF
 93.0 41
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
b-NGF
 79.0 47
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
b-NGF
 71.5 56
N2586 Sigma A6730 3.0
uM
 1
b-NGF
 96.0 42
RA2159 IL-17A 100
ng/mL
 1
b-NGF
 48.0 69
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
b-NGF
 54.0 53
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
b-NGF
 40.0 57
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
b-NGF
 45.0 82
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
b-NGF
 61.5 62
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
b-NGF
 48.0 53
N2586 IL-17A 100
ng/mL
 1
b-NGF
 112.0 42
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
b-NGF
 112.0 41
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
b-NGF
 101.0 31
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
b-NGF
 74.5 40
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
b-NGF
 84.0 40
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
b-NGF
 65.0 50
RA2159 1
b-NGF
 51.0 36
RA2159 PD184352 0.1
uM
 1
b-NGF
 49.5 60
RA2159 Lestaurtinib 0.3
uM
 1
b-NGF
 33.5 68
RA2159 Ruxolitinib 0.3
uM
 1
b-NGF
 43.0 87
RA2159 Tofacitinib 0.3
uM
 1
b-NGF
 40.0 79
RA2159 IKK16 2.0
uM
 1
b-NGF
 38.0 63
RA2159 JNK-IN-8 3.0
uM
 1
b-NGF
 34.5 48
N2586 1
b-NGF
 81.5 44