Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Ruxolitinib 0.3
uM
 3
IL18
 18.0 61
RA2159 Tofacitinib 0.3
uM
 3
IL18
 16.0 79
RA2159 IKK16 2.0
uM
 3
IL18
 19.0 55
RA2159 JNK-IN-8 3.0
uM
 3
IL18
 17.5 88
N2586 3
IL18
 68.0 74
N2586 PD184352 0.1
uM
 3
IL18
 76.5 76
N2586 Lestaurtinib 0.3
uM
 3
IL18
 49.0 74
N2586 Ruxolitinib 0.3
uM
 3
IL18
 98.5 76
N2586 Tofacitinib 0.3
uM
 3
IL18
 55.0 72
N2586 IKK16 2.0
uM
 3
IL18
 49.0 53
N2586 JNK-IN-8 3.0
uM
 3
IL18
 52.0 64
RA2159 IL-17A 100
ng/mL
 3
IL18
 19.0 75
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IL18
 20.5 78
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL18
 17.0 77
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL18
 21.5 68
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL18
 18.0 87
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL18
 20.0 83
N2586 IL-17A 100
ng/mL
 3
IL18
 70.0 72
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IL18
 72.0 75
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL18
 50.0 58
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL18
 123.0 69
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL18
 48.5 70
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL18
 46.0 68
RA2159 IL-6 100
ug/mL
 3
IL18
 19.0 80
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IL18
 18.0 71