Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Lestaurtinib 0.3
uM
 EGF 100
ng/mL
 3
MIF
 55.0 76
N2586 Ruxolitinib 0.3
uM
 EGF 100
ng/mL
 3
MIF
 81.0 61
N2586 Tofacitinib 0.3
uM
 EGF 100
ng/mL
 3
MIF
 56.0 63
N2586 IKK16 2.0
uM
 EGF 100
ng/mL
 3
MIF
 46.5 64
N2586 JNK-IN-11 0.3
uM
 3
MIF
 29.0 55
RA2159 3
MIF
 21.0 66
RA2159 PD184352 0.1
uM
 3
MIF
 18.0 55
RA2159 Lestaurtinib 0.3
uM
 3
MIF
 17.0 61
RA2159 Ruxolitinib 0.3
uM
 3
MIF
 20.0 64
RA2159 Tofacitinib 0.3
uM
 3
MIF
 19.0 65
RA2159 IKK16 2.0
uM
 3
MIF
 20.5 64
RA2159 JNK-IN-8 3.0
uM
 3
MIF
 17.0 69
N2586 3
MIF
 56.0 72
N2586 PD184352 0.1
uM
 3
MIF
 73.5 54
N2586 Lestaurtinib 0.3
uM
 3
MIF
 48.0 70
N2586 Ruxolitinib 0.3
uM
 3
MIF
 72.0 65
N2586 Tofacitinib 0.3
uM
 3
MIF
 60.0 71
N2586 IKK16 2.0
uM
 3
MIF
 44.0 57
N2586 JNK-IN-8 3.0
uM
 3
MIF
 42.0 52
RA2159 IL-17A 100
ng/mL
 3
MIF
 16.5 68
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
MIF
 17.0 64
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIF
 22.0 61
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIF
 20.5 54
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIF
 20.0 57
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
MIF
 18.0 59