Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIF
 21.5 48
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
MIF
 21.0 50
N2586 IL-17A 100
ng/mL
 1
MIF
 68.0 41
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
MIF
 57.0 43
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIF
 59.0 38
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIF
 56.0 37
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIF
 46.5 48
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
MIF
 51.5 40
RA2159 1
MIF
 18.5 36
RA2159 PD184352 0.1
uM
 1
MIF
 23.0 53
RA2159 Lestaurtinib 0.3
uM
 1
MIF
 24.0 55
RA2159 Ruxolitinib 0.3
uM
 1
MIF
 20.0 65
RA2159 Tofacitinib 0.3
uM
 1
MIF
 24.5 58
RA2159 IKK16 2.0
uM
 1
MIF
 21.0 57
RA2159 JNK-IN-8 3.0
uM
 1
MIF
 17.5 40
N2586 1
MIF
 48.0 49
N2586 PD184352 0.1
uM
 1
MIF
 46.0 59
N2586 Lestaurtinib 0.3
uM
 1
MIF
 47.0 52
N2586 Ruxolitinib 0.3
uM
 1
MIF
 52.0 53
N2586 Tofacitinib 0.3
uM
 1
MIF
 49.0 47
N2586 IKK16 2.0
uM
 1
MIF
 37.0 63
N2586 JNK-IN-8 3.0
uM
 1
MIF
 41.0 35
RA2159 EGF 100
ng/mL
 1
MIF
 20.0 63
RA2159 PD184352 0.1
uM
 EGF 100
ng/mL
 1
MIF
 20.5 66
RA2159 Lestaurtinib 0.3
uM
 EGF 100
ng/mL
 1
MIF
 19.0 69