Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Lestaurtinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 48.0 60
RA2159 Ruxolitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 57.0 73
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 48.0 79
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 50.0 71
N2586 Poly(I:C) 2
ug/mL
 3
TNFb
 53.5 52
N2586 PD184352 0.1
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 132.0 58
N2586 Lestaurtinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 58.0 71
N2586 Ruxolitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 33.5 52
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 39.0 40
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 57.0 49
RA2159 3
TNFb
 0
RA2159 PD184352 0.1
uM
 3
TNFb
 0
RA2159 Lestaurtinib 0.3
uM
 3
TNFb
 0
RA2159 Ruxolitinib 0.3
uM
 3
TNFb
 0
RA2159 Tofacitinib 0.3
uM
 3
TNFb
 0
RA2159 IKK16 2.0
uM
 3
TNFb
 0
RA2159 3
TNFb
 0
N2586 3
TNFb
 0
N2586 PD184352 0.1
uM
 3
TNFb
 0
N2586 Lestaurtinib 0.3
uM
 3
TNFb
 0
N2586 Ruxolitinib 0.3
uM
 3
TNFb
 0
N2586 Tofacitinib 0.3
uM
 3
TNFb
 0
N2586 IKK16 2.0
uM
 3
TNFb
 0
N2586 3
TNFb
 0
RA2159 Visfatin 1
ng/mL
 3
TNFb
 97.5 50