Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2159 | 1 | TNFb | 43.0 | 50 | |||||||
N2586 | IGF-I | 100 | ug/mL | 1 | TNFb | 67.5 | 48 | ||||
N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | TNFb | 46.5 | 68 | |
N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | TNFb | 50.0 | 55 | |
N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | TNFb | 47.0 | 45 | |
N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | TNFb | 48.0 | 21 | |
N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | TNFb | 55.0 | 51 | |
N2586 | 1 | TNFb | 39.0 | 33 | |||||||
RA2159 | Adiponectin | 5 | ng/mL | 1 | TNFb | 84.0 | 54 | ||||
RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 79.5 | 60 | |
RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 94.5 | 52 | |
RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 81.0 | 62 | |
RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 98.0 | 60 | |
RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 92.5 | 54 | |
N2586 | Adiponectin | 5 | ng/mL | 1 | TNFb | 80.0 | 60 | ||||
N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 85.0 | 59 | |
N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 82.0 | 43 | |
N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 67.5 | 42 | |
N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 110.0 | 50 | |
N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | TNFb | 58.0 | 45 | |
RA2159 | Leptin | 1 | ng/mL | 1 | TNFb | 46.0 | 51 | ||||
RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | TNFb | 35.5 | 46 | |
RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | TNFb | 40.0 | 44 | |
RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | TNFb | 64.0 | 58 | |
RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | TNFb | 41.0 | 36 |