Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 8779.0 62
RA2159 Tofacitinib 0.3
uM
 Visfatin 1
ng/mL
 1
MIP-1B
 63.0 43
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 8762.0 53
N2586 JNK-IN-11 0.3
uM
 Leptin 1
ng/mL
 2
MIP-1B
 61.0 80
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 25570.0 61
TNF-a 100
ng/mL
 0
IL-1RA
 82.0 70
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-1RA
 21.5 44
RA2159 TNF-a 100
ng/mL
 4
IL-1RA
 47.0 65
RA2159 EO1428 1.0
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 41.0 57
RA2159 Lestaurtinib 0.3
uM
 EGF 100
ng/mL
 3
GM-CSF
 168.0 45
RA2159 IKK16 2.0
uM
 Visfatin 1
ng/mL
 1
MIP-1B
 62.5 78
N2586 EO1428 1.0
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 52.0 49
N2586 TNF-a 100
ng/mL
 4
IL-1RA
 47.0 38
RA2159 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 34.5 64
RA2159 Adiponectin 5
ng/mL
 2
IL-1RA
 23.0 73
RA2159 EO1428 1.0
uM
 Adiponectin 5
ng/mL
 2
IL-1RA
 19.0 69
RA2159 PI103 0.1
uM
 Adiponectin 5
ng/mL
 2
IL-1RA
 21.0 61
RA2159 Sigma A6730 3.0
uM
 Adiponectin 5
ng/mL
 2
IL-1RA
 22.0 66
RA2159 JNK-IN-8 3.0
uM
 Adiponectin 5
ng/mL
 2
IL-1RA
 19.0 50
RA2159 JNK-IN-11 0.3
uM
 Adiponectin 5
ng/mL
 2
IL-1RA
 24.0 53
N2586 Adiponectin 5
ng/mL
 2
IL-1RA
 22.0 66
N2586 EO1428 1.0
uM
 Adiponectin 5
ng/mL
 2
IL-1RA
 22.5 50
N2586 PI103 0.1
uM
 Adiponectin 5
ng/mL
 2
IL-1RA
 25.0 44
Adiponectin 5
ng/mL
 0
TNF-a
 24.0 78
EGF 100
ng/mL
 0
TNF-a
 18.0 86