Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
MCP3
 22.0 66
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
MCP3
 24.5 52
RA2159 Sigma A6730 3.0
uM
 3
MCP3
 28.0 70
N2586 IL-6 100
ug/mL
 3
MCP3
 72.0 76
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
MCP3
 58.0 59
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
MCP3
 44.0 67
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
MCP3
 70.5 58
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
MCP3
 42.0 61
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
MCP3
 45.0 73
N2586 Sigma A6730 3.0
uM
 3
MCP3
 54.0 51
RA2159 IL-1 alpha 100
ng/mL
 3
MCP3
 236.5 68
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 55.0 49
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 76.0 76
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 188.0 72
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 169.0 62
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 26.0 60
RA2159 PI103 0.1
uM
 3
MCP3
 24.0 59
N2586 IL-1 alpha 100
ng/mL
 3
MCP3
 818.0 69
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 339.0 59
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 651.0 61
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 773.0 50
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 71.5 52
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 326.0 71
N2586 PI103 0.1
uM
 3
MCP3
 43.0 61
0
MCP3
 17.0 63