Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 1
TNFb
 53.0 62
RA2159 IKK16 2.0
uM
 1
TNFb
 53.5 58
RA2159 1
TNFb
 50.0 70
N2586 1
TNFb
 70.0 61
N2586 PD184352 0.1
uM
 1
TNFb
 52.0 54
N2586 Lestaurtinib 0.3
uM
 1
TNFb
 46.0 67
N2586 Ruxolitinib 0.3
uM
 1
TNFb
 50.0 55
N2586 Tofacitinib 0.3
uM
 1
TNFb
 62.0 61
N2586 IKK16 2.0
uM
 1
TNFb
 45.0 39
N2586 1
TNFb
 47.0 35
0
TNFb
 79.0 51
0
TNFb
 43.0 38
RA2159 TNF-a 100
ng/mL
 1
TNFb
 49.0 50
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
TNFb
 56.0 77
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
TNFb
 45.0 70
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
TNFb
 41.0 50
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
TNFb
 57.0 43
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
TNFb
 55.0 45
RA2159 EO1428 1.0
uM
 1
TNFb
 64.0 50
N2586 TNF-a 100
ng/mL
 1
TNFb
 64.0 49
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
TNFb
 88.0 47
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
TNFb
 43.0 33
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
TNFb
 60.0 64
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
TNFb
 74.0 53
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
TNFb
 50.0 35