Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
MIG
 18.5 68
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
MIG
 17.0 62
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
MIG
 20.0 51
RA2159 Ruxolitinib 0.3
uM
 2
MIG
 19.0 60
N2586 IL-6 100
ug/mL
 2
MIG
 49.0 61
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
MIG
 49.5 84
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 2
MIG
 40.0 60
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
MIG
 51.0 70
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
MIG
 33.0 61
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
MIG
 37.0 41
N2586 Ruxolitinib 0.3
uM
 2
MIG
 43.0 57
RA2159 IL-17A 100
ng/mL
 2
MIG
 19.0 65
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
MIG
 27.0 52
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
MIG
 21.0 61
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
MIG
 25.0 65
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
MIG
 20.0 51
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
MIG
 22.0 35
RA2159 Tofacitinib 0.3
uM
 2
MIG
 15.0 31
N2586 IL-17A 100
ng/mL
 2
MIG
 60.0 39
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
MIG
 60.0 59
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
MIG
 48.0 13
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
MIG
 67.0 28
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
MIG
 37.5 50
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
MIG
 41.5 50
N2586 Tofacitinib 0.3
uM
 2
MIG
 35.5 74