Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
MIG
 65.0 45
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MIG
 54.0 22
0
MIG
 17.5 40
RA2159 2
MIG
 17.0 66
RA2159 EO1428 1.0
uM
 2
MIG
 19.5 60
RA2159 PI103 0.1
uM
 2
MIG
 13.0 61
RA2159 Sigma A6730 3.0
uM
 2
MIG
 16.0 82
RA2159 JNK-IN-8 3.0
uM
 2
MIG
 14.0 64
RA2159 JNK-IN-11 0.3
uM
 2
MIG
 19.5 68
RA2159 2
MIG
 18.0 65
N2586 2
MIG
 38.0 48
N2586 EO1428 1.0
uM
 2
MIG
 45.0 55
N2586 PI103 0.1
uM
 2
MIG
 42.5 70
N2586 Sigma A6730 3.0
uM
 2
MIG
 45.5 40
N2586 JNK-IN-8 3.0
uM
 2
MIG
 36.0 55
N2586 JNK-IN-11 0.3
uM
 2
MIG
 43.0 40
N2586 2
MIG
 50.0 60
0
MIG
 11.0 53
0
MIG
 13.0 59
RA2159 TNF-a 100
ng/mL
 2
MIG
 68.5 62
RA2159 EO1428 1.0
uM
 TNF-a 100
ng/mL
 2
MIG
 60.5 64
RA2159 PI103 0.1
uM
 TNF-a 100
ng/mL
 2
MIG
 63.0 77
RA2159 Sigma A6730 3.0
uM
 TNF-a 100
ng/mL
 2
MIG
 61.5 58
RA2159 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
MIG
 48.0 54
RA2159 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 2
MIG
 41.0 69