Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
MIG
 17.0 58
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
MIG
 17.0 55
RA2159 Sigma A6730 3.0
uM
 1
MIG
 20.0 58
N2586 IL-6 100
ug/mL
 1
MIG
 48.5 70
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
MIG
 44.0 68
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
MIG
 36.0 63
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
MIG
 45.0 47
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
MIG
 35.0 55
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
MIG
 47.0 44
N2586 Sigma A6730 3.0
uM
 1
MIG
 56.0 53
RA2159 IL-17A 100
ng/mL
 1
MIG
 16.0 50
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
MIG
 19.0 70
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIG
 18.0 62
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIG
 18.0 69
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIG
 20.0 56
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
MIG
 18.0 68
N2586 IL-17A 100
ng/mL
 1
MIG
 70.0 37
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
MIG
 57.0 30
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIG
 52.0 30
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIG
 59.0 46
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
MIG
 48.0 43
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
MIG
 46.5 64
RA2159 1
MIG
 18.0 52
RA2159 PD184352 0.1
uM
 1
MIG
 23.0 75
RA2159 Lestaurtinib 0.3
uM
 1
MIG
 15.0 76