Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 TNF-a 100
ng/mL
 1
MIG
 191.5 70
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
MIG
 181.5 48
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIG
 136.0 37
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIG
 204.0 54
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIG
 198.5 54
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MIG
 172.0 43
N2586 EO1428 1.0
uM
 1
MIG
 45.0 57
RA2159 IL-1 alpha 100
ng/mL
 1
MIG
 40.0 78
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 40.5 80
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 48.5 48
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 43.0 51
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 39.0 79
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 19.5 50
RA2159 PI103 0.1
uM
 1
MIG
 18.0 53
N2586 IL-1 alpha 100
ng/mL
 1
MIG
 131.0 45
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 123.0 47
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 186.0 52
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 151.0 57
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 128.0 52
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 78.0 47
N2586 PI103 0.1
uM
 1
MIG
 35.0 38
RA2159 IL-6 100
ug/mL
 1
MIG
 18.5 68
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
MIG
 17.0 50
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
MIG
 17.0 45
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
MIG
 18.0 59