Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
2
IL-17
50.0 71
RA2159 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
2
IL-17
53.0 85
RA2159 Ruxolitinib 0.3
uM
2
IL-17
46.0 43
N2586 IL-6 100
ug/mL
2
IL-17
53.5 60
N2586 EO1428 1.0
uM
IL-6 100
ug/mL
2
IL-17
52.0 74
N2586 PI103 0.1
uM
IL-6 100
ug/mL
2
IL-17
53.0 61
N2586 Sigma A6730 3.0
uM
IL-6 100
ug/mL
2
IL-17
54.0 54
N2586 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
2
IL-17
49.0 65
N2586 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
2
IL-17
53.0 49
N2586 Ruxolitinib 0.3
uM
2
IL-17
58.0 57
RA2159 IL-17A 100
ng/mL
2
IL-17
2288.0 67
RA2159 EO1428 1.0
uM
IL-17A 100
ng/mL
2
IL-17
3183.0 63
RA2159 PI103 0.1
uM
IL-17A 100
ng/mL
2
IL-17
2494.0 71
RA2159 Sigma A6730 3.0
uM
IL-17A 100
ng/mL
2
IL-17
3040.5 56
RA2159 JNK-IN-8 3.0
uM
IL-17A 100
ng/mL
2
IL-17
2160.0 65
RA2159 JNK-IN-11 0.3
uM
IL-17A 100
ng/mL
2
IL-17
2078.0 49
RA2159 Tofacitinib 0.3
uM
2
IL-17
52.0 57
N2586 IL-17A 100
ng/mL
2
IL-17
2749.0 47
N2586 EO1428 1.0
uM
IL-17A 100
ng/mL
2
IL-17
3147.5 58
N2586 PI103 0.1
uM
IL-17A 100
ng/mL
2
IL-17
1788.0 69
N2586 Sigma A6730 3.0
uM
IL-17A 100
ng/mL
2
IL-17
3070.0 81
N2586 JNK-IN-8 3.0
uM
IL-17A 100
ng/mL
2
IL-17
1976.5 64
N2586 JNK-IN-11 0.3
uM
IL-17A 100
ng/mL
2
IL-17
2118.0 80
N2586 Tofacitinib 0.3
uM
2
IL-17
61.0 56
RA2159 2
IL-17
53.5 52