Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 65.0 | 67 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 52.0 | 63 | |
| RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 56.0 | 73 | |
| RA2159 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 58.5 | 62 | |
| RA2159 | 3 | IL-12 (p70) | 59.0 | 62 | |||||||
| N2586 | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 79.5 | 56 | ||||
| N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 67.0 | 67 | |
| N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 64.0 | 77 | |
| N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 91.0 | 65 | |
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 77.0 | 75 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 82.5 | 68 | |
| N2586 | 3 | IL-12 (p70) | 75.0 | 72 | |||||||
| RA2159 | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 51.0 | 68 | ||||
| RA2159 | PD184352 | 0.1 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 45.0 | 65 | |
| RA2159 | Lestaurtinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 58.0 | 58 | |
| RA2159 | Ruxolitinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 59.0 | 41 | |
| RA2159 | Tofacitinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 37.0 | 75 | |
| RA2159 | IKK16 | 2.0 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 46.5 | 48 | |
| RA2159 | JNK-IN-11 | 0.3 | uM | 3 | IL-12 (p70) | 54.0 | 81 | ||||
| N2586 | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 92.5 | 56 | ||||
| N2586 | PD184352 | 0.1 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 71.5 | 78 | |
| N2586 | Lestaurtinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 70.0 | 53 | |
| N2586 | Ruxolitinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 78.0 | 59 | |
| N2586 | Tofacitinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 62.5 | 66 | |
| N2586 | IKK16 | 2.0 | uM | EGF | 100 | ng/mL | 3 | IL-12 (p70) | 67.0 | 63 |