Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-11 0.3
uM
3
IL-12 (p70)
42.0 39
RA2159 3
IL-12 (p70)
46.0 60
RA2159 PD184352 0.1
uM
3
IL-12 (p70)
68.0 53
RA2159 Lestaurtinib 0.3
uM
3
IL-12 (p70)
55.5 54
RA2159 Ruxolitinib 0.3
uM
3
IL-12 (p70)
49.0 58
RA2159 Tofacitinib 0.3
uM
3
IL-12 (p70)
43.0 67
RA2159 IKK16 2.0
uM
3
IL-12 (p70)
44.0 71
RA2159 JNK-IN-8 3.0
uM
3
IL-12 (p70)
36.0 69
N2586 3
IL-12 (p70)
62.5 62
N2586 PD184352 0.1
uM
3
IL-12 (p70)
57.0 58
N2586 Lestaurtinib 0.3
uM
3
IL-12 (p70)
52.0 72
N2586 Ruxolitinib 0.3
uM
3
IL-12 (p70)
65.0 67
N2586 Tofacitinib 0.3
uM
3
IL-12 (p70)
84.5 68
N2586 IKK16 2.0
uM
3
IL-12 (p70)
51.0 67
N2586 JNK-IN-8 3.0
uM
3
IL-12 (p70)
75.0 53
RA2159 IL-17A 100
ng/mL
3
IL-12 (p70)
53.0 54
RA2159 PD184352 0.1
uM
IL-17A 100
ng/mL
3
IL-12 (p70)
93.0 69
RA2159 Lestaurtinib 0.3
uM
IL-17A 100
ng/mL
3
IL-12 (p70)
60.0 72
RA2159 Ruxolitinib 0.3
uM
IL-17A 100
ng/mL
3
IL-12 (p70)
56.0 75
RA2159 Tofacitinib 0.3
uM
IL-17A 100
ng/mL
3
IL-12 (p70)
52.5 60
RA2159 IKK16 2.0
uM
IL-17A 100
ng/mL
3
IL-12 (p70)
55.0 67
N2586 IL-17A 100
ng/mL
3
IL-12 (p70)
65.0 64
N2586 PD184352 0.1
uM
IL-17A 100
ng/mL
3
IL-12 (p70)
70.0 84
N2586 Lestaurtinib 0.3
uM
IL-17A 100
ng/mL
3
IL-12 (p70)
31.0 58
N2586 Ruxolitinib 0.3
uM
IL-17A 100
ng/mL
3
IL-12 (p70)
59.0 71