Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 41.0 | 66 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 31.5 | 70 | |
| N2586 | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 55.5 | 72 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 60.5 | 62 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 65.0 | 45 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 41.0 | 43 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 45.0 | 54 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 59.0 | 48 | |
| RA2159 | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 38.5 | 58 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 36.0 | 47 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 51.0 | 71 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 44.0 | 58 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 39.5 | 62 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 38.0 | 51 | |
| N2586 | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 52.0 | 51 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 51.0 | 66 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 57.5 | 68 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 51.0 | 68 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 45.0 | 51 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | IL-12 (p70) | 45.0 | 35 | |
| RA2159 | 1 | IL-12 (p70) | 48.5 | 58 | |||||||
| RA2159 | PD184352 | 0.1 | uM | 1 | IL-12 (p70) | 60.5 | 62 | ||||
| RA2159 | Lestaurtinib | 0.3 | uM | 1 | IL-12 (p70) | 52.0 | 73 | ||||
| RA2159 | Ruxolitinib | 0.3 | uM | 1 | IL-12 (p70) | 53.0 | 61 | ||||
| RA2159 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 44.0 | 67 |