Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-8
 11862.0 55
N2586 Lestaurtinib 0.3
uM
 2
IL-8
 457.0 56
RA2159 IL-6 100
ug/mL
 2
IL-8
 545.5 88
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
IL-8
 912.5 54
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 2
IL-8
 685.0 63
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
IL-8
 802.5 64
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
IL-8
 235.0 57
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
IL-8
 497.5 72
RA2159 Ruxolitinib 0.3
uM
 2
IL-8
 489.0 58
N2586 IL-6 100
ug/mL
 2
IL-8
 587.0 79
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
IL-8
 344.0 90
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 2
IL-8
 676.5 68
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
IL-8
 1353.0 65
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
IL-8
 337.0 74
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
IL-8
 593.0 46
N2586 Ruxolitinib 0.3
uM
 2
IL-8
 842.0 58
RA2159 IL-17A 100
ng/mL
 2
IL-8
 1029.5 78
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL-8
 1347.0 86
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL-8
 1606.0 78
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL-8
 2279.0 60
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IL-8
 420.0 55
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IL-8
 1366.5 56
RA2159 Tofacitinib 0.3
uM
 2
IL-8
 512.0 76
N2586 IL-17A 100
ng/mL
 2
IL-8
 1800.5 54
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL-8
 966.5 68