Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IL-1 alpha 100
ng/mL
 2
IL-2
 70.0 50
N2586 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 53.0 89
N2586 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 68.0 79
N2586 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 69.0 84
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 68.0 65
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 67.0 69
N2586 Lestaurtinib 0.3
uM
 2
IL-2
 39.0 57
RA2159 IL-6 100
ug/mL
 2
IL-2
 49.0 84
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
IL-2
 49.0 56
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 2
IL-2
 43.5 72
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
IL-2
 46.5 62
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
IL-2
 46.0 84
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
IL-2
 44.5 88
RA2159 Ruxolitinib 0.3
uM
 2
IL-2
 40.0 54
N2586 IL-6 100
ug/mL
 2
IL-2
 45.5 70
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
IL-2
 45.5 80
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 2
IL-2
 47.0 74
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
IL-2
 40.0 65
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
IL-2
 42.5 72
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
IL-2
 41.0 68
N2586 Ruxolitinib 0.3
uM
 2
IL-2
 42.5 64
RA2159 IL-17A 100
ng/mL
 2
IL-2
 45.5 78
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL-2
 46.0 95
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL-2
 40.5 90
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL-2
 40.0 76