Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 PD184352 0.1
uM
 3
SCF
 31.0 67
RA2159 Lestaurtinib 0.3
uM
 3
SCF
 30.0 61
RA2159 Ruxolitinib 0.3
uM
 3
SCF
 39.0 73
RA2159 Tofacitinib 0.3
uM
 3
SCF
 34.0 65
RA2159 IKK16 2.0
uM
 3
SCF
 34.0 51
RA2159 JNK-IN-8 3.0
uM
 3
SCF
 34.0 84
N2586 3
SCF
 65.5 62
N2586 PD184352 0.1
uM
 3
SCF
 72.0 65
N2586 Lestaurtinib 0.3
uM
 3
SCF
 57.0 79
N2586 Ruxolitinib 0.3
uM
 3
SCF
 96.0 73
N2586 Tofacitinib 0.3
uM
 3
SCF
 70.0 75
N2586 IKK16 2.0
uM
 3
SCF
 53.0 60
N2586 JNK-IN-8 3.0
uM
 3
SCF
 50.5 58
RA2159 IL-17A 100
ng/mL
 3
SCF
 40.0 93
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
SCF
 34.0 78
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
SCF
 36.5 68
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
SCF
 34.0 61
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
SCF
 36.0 69
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
SCF
 34.0 76
N2586 IL-17A 100
ng/mL
 3
SCF
 70.5 76
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
SCF
 78.0 87
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
SCF
 60.5 66
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
SCF
 122.0 69
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
SCF
 51.0 72
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
SCF
 50.0 78