Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 137.0 74
N2586 Lestaurtinib 0.3
uM
 2
SCF
 56.0 61
RA2159 IL-6 100
ug/mL
 2
SCF
 50.0 52
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
SCF
 39.0 59
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 2
SCF
 47.0 83
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
SCF
 43.0 65
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
SCF
 38.5 84
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
SCF
 40.5 38
RA2159 Ruxolitinib 0.3
uM
 2
SCF
 43.0 59
N2586 IL-6 100
ug/mL
 2
SCF
 61.0 83
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
SCF
 62.0 64
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 2
SCF
 63.0 66
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
SCF
 62.5 84
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
SCF
 49.0 63
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
SCF
 51.0 69
N2586 Ruxolitinib 0.3
uM
 2
SCF
 55.0 63
RA2159 IL-17A 100
ng/mL
 2
SCF
 43.0 82
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
SCF
 46.5 66
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
SCF
 43.0 78
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
SCF
 46.0 81
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
SCF
 38.0 59
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
SCF
 40.0 35
RA2159 Tofacitinib 0.3
uM
 2
SCF
 47.0 29
N2586 IL-17A 100
ng/mL
 2
SCF
 81.5 38
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
SCF
 79.0 75