Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
4
IL3
34.0 34
N2586 IL-17A 100
ng/mL
4
IL3
40.0 61
N2586 EO1428 1.0
uM
IL-17A 100
ng/mL
4
IL3
41.0 58
N2586 PI103 0.1
uM
IL-17A 100
ng/mL
4
IL3
43.5 50
N2586 Sigma A6730 3.0
uM
IL-17A 100
ng/mL
4
IL3
39.0 56
N2586 JNK-IN-8 3.0
uM
IL-17A 100
ng/mL
4
IL3
38.0 73
N2586 JNK-IN-11 0.3
uM
IL-17A 100
ng/mL
4
IL3
34.0 69
N2586 Tofacitinib 0.3
uM
4
IL3
38.0 54
RA2159 IL-6 100
ug/mL
4
IL3
180.5 80
RA2159 EO1428 1.0
uM
IL-6 100
ug/mL
4
IL3
38.0 89
RA2159 PI103 0.1
uM
IL-6 100
ug/mL
4
IL3
41.0 66
RA2159 Sigma A6730 3.0
uM
IL-6 100
ug/mL
4
IL3
37.5 66
RA2159 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
4
IL3
37.0 64
RA2159 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
4
IL3
40.0 65
RA2159 Ruxolitinib 0.3
uM
4
IL3
31.0 72
N2586 IL-6 100
ug/mL
4
IL3
37.0 59
N2586 EO1428 1.0
uM
IL-6 100
ug/mL
4
IL3
52.0 50
N2586 PI103 0.1
uM
IL-6 100
ug/mL
4
IL3
40.0 52
N2586 Sigma A6730 3.0
uM
IL-6 100
ug/mL
4
IL3
43.0 58
N2586 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
4
IL3
37.0 63
N2586 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
4
IL3
36.0 63
N2586 Ruxolitinib 0.3
uM
4
IL3
39.0 80
RA2159 IL-1 alpha 100
ng/mL
4
IL3
56.0 77
RA2159 EO1428 1.0
uM
IL-1 alpha 100
ng/mL
4
IL3
45.0 87
RA2159 PI103 0.1
uM
IL-1 alpha 100
ng/mL
4
IL3
184.5 64