Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Sigma A6730 3.0
uM
 TNF-a 100
ng/mL
 2
IL1-a
 79.5 42
N2586 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
IL1-a
 97.0 58
N2586 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 2
IL1-a
 77.5 40
N2586 PD184352 0.1
uM
 2
IL1-a
 71.5 42
RA2159 IL-1 alpha 100
ng/mL
 2
IL1-a
 25457.0 65
RA2159 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 25298.0 57
RA2159 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 26322.0 69
RA2159 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 26106.0 60
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 26390.0 67
RA2159 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 20475.0 61
RA2159 Lestaurtinib 0.3
uM
 2
IL1-a
 56.0 57
N2586 IL-1 alpha 100
ng/mL
 2
IL1-a
 19156.0 63
N2586 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 23432.5 58
N2586 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 16401.0 45
N2586 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 17108.0 53
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 18996.0 54
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 18086.0 47
N2586 Lestaurtinib 0.3
uM
 2
IL1-a
 76.0 57
RA2159 IL-6 100
ug/mL
 2
IL1-a
 232.5 74
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
IL1-a
 52.0 61
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 2
IL1-a
 151.0 61
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
IL1-a
 62.0 61
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
IL1-a
 62.0 57
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
IL1-a
 80.0 37
RA2159 Ruxolitinib 0.3
uM
 2
IL1-a
 62.0 57