Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2586 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 1 | IL1-a | 70.0 | 61 | |
N2586 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL1-a | 51.5 | 40 | |
N2586 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL1-a | 59.0 | 37 | |
N2586 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL1-a | 64.0 | 53 | |
N2586 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 1 | IL1-a | 62.5 | 70 | |
N2586 | Sigma A6730 | 3.0 | uM | 1 | IL1-a | 74.0 | 60 | ||||
RA2159 | IL-17A | 100 | ng/mL | 1 | IL1-a | 81.0 | 62 | ||||
RA2159 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 56.0 | 57 | |
RA2159 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 51.5 | 50 | |
RA2159 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 58.0 | 85 | |
RA2159 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 55.5 | 60 | |
RA2159 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 57.0 | 55 | |
N2586 | IL-17A | 100 | ng/mL | 1 | IL1-a | 65.0 | 29 | ||||
N2586 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 55.0 | 39 | |
N2586 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 103.0 | 29 | |
N2586 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 85.0 | 29 | |
N2586 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 56.5 | 32 | |
N2586 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | IL1-a | 73.0 | 41 | |
RA2159 | 1 | IL1-a | 62.0 | 45 | |||||||
RA2159 | PD184352 | 0.1 | uM | 1 | IL1-a | 251.0 | 72 | ||||
RA2159 | Lestaurtinib | 0.3 | uM | 1 | IL1-a | 82.0 | 73 | ||||
RA2159 | Ruxolitinib | 0.3 | uM | 1 | IL1-a | 55.0 | 85 | ||||
RA2159 | Tofacitinib | 0.3 | uM | 1 | IL1-a | 57.0 | 81 | ||||
RA2159 | IKK16 | 2.0 | uM | 1 | IL1-a | 53.0 | 58 | ||||
RA2159 | JNK-IN-8 | 3.0 | uM | 1 | IL1-a | 68.0 | 42 |