Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Lestaurtinib 0.3
uM
 3
HGF
 29.0 63
RA2159 Ruxolitinib 0.3
uM
 3
HGF
 38.0 70
RA2159 Tofacitinib 0.3
uM
 3
HGF
 35.0 65
RA2159 IKK16 2.0
uM
 3
HGF
 34.5 48
RA2159 JNK-IN-8 3.0
uM
 3
HGF
 36.0 84
N2586 3
HGF
 55.0 51
N2586 PD184352 0.1
uM
 3
HGF
 60.0 92
N2586 Lestaurtinib 0.3
uM
 3
HGF
 45.0 85
N2586 Ruxolitinib 0.3
uM
 3
HGF
 73.5 68
N2586 Tofacitinib 0.3
uM
 3
HGF
 54.0 57
N2586 IKK16 2.0
uM
 3
HGF
 42.0 73
N2586 JNK-IN-8 3.0
uM
 3
HGF
 43.5 50
RA2159 IL-17A 100
ng/mL
 3
HGF
 41.0 75
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
HGF
 40.5 62
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
HGF
 32.5 68
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
HGF
 41.0 59
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
HGF
 40.0 73
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
HGF
 38.0 56
N2586 IL-17A 100
ng/mL
 3
HGF
 57.0 65
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
HGF
 67.5 60
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
HGF
 48.0 80
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
HGF
 88.5 82
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
HGF
 44.5 68
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
HGF
 45.0 55
RA2159 IL-6 100
ug/mL
 3
HGF
 50.0 63