Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Lestaurtinib 0.3
uM
2
HGF
42.0 78
RA2159 IL-6 100
ug/mL
2
HGF
45.0 75
RA2159 EO1428 1.0
uM
IL-6 100
ug/mL
2
HGF
36.0 71
RA2159 PI103 0.1
uM
IL-6 100
ug/mL
2
HGF
40.0 69
RA2159 Sigma A6730 3.0
uM
IL-6 100
ug/mL
2
HGF
36.0 70
RA2159 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
2
HGF
38.0 70
RA2159 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
2
HGF
41.0 41
RA2159 Ruxolitinib 0.3
uM
2
HGF
41.0 59
N2586 IL-6 100
ug/mL
2
HGF
54.0 55
N2586 EO1428 1.0
uM
IL-6 100
ug/mL
2
HGF
50.0 75
N2586 PI103 0.1
uM
IL-6 100
ug/mL
2
HGF
44.0 67
N2586 Sigma A6730 3.0
uM
IL-6 100
ug/mL
2
HGF
51.5 56
N2586 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
2
HGF
40.0 59
N2586 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
2
HGF
43.0 42
N2586 Ruxolitinib 0.3
uM
2
HGF
46.0 41
RA2159 IL-17A 100
ng/mL
2
HGF
42.0 75
RA2159 EO1428 1.0
uM
IL-17A 100
ng/mL
2
HGF
39.0 63
RA2159 PI103 0.1
uM
IL-17A 100
ng/mL
2
HGF
36.5 62
RA2159 Sigma A6730 3.0
uM
IL-17A 100
ng/mL
2
HGF
39.5 76
RA2159 JNK-IN-8 3.0
uM
IL-17A 100
ng/mL
2
HGF
40.5 52
RA2159 JNK-IN-11 0.3
uM
IL-17A 100
ng/mL
2
HGF
42.5 42
RA2159 Tofacitinib 0.3
uM
2
HGF
49.0 45
N2586 IL-17A 100
ng/mL
2
HGF
55.5 52
N2586 EO1428 1.0
uM
IL-17A 100
ng/mL
2
HGF
60.5 86
N2586 PI103 0.1
uM
IL-17A 100
ng/mL
2
HGF
51.0 23