Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IKK16 2.0
uM
 4
b-NGF
 62.0 62
RA2159 IL-17A 100
ng/mL
 4
b-NGF
 44.5 50
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 4
b-NGF
 45.0 62
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 4
b-NGF
 45.0 71
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 4
b-NGF
 45.5 72
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 4
b-NGF
 49.0 70
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 4
b-NGF
 36.0 45
RA2159 Tofacitinib 0.3
uM
 4
b-NGF
 47.5 28
N2586 IL-17A 100
ng/mL
 4
b-NGF
 128.0 41
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 4
b-NGF
 137.0 62
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 4
b-NGF
 95.5 40
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 4
b-NGF
 100.5 46
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 4
b-NGF
 79.5 58
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 4
b-NGF
 72.0 66
N2586 Tofacitinib 0.3
uM
 4
b-NGF
 49.5 50
RA2159 IL-6 100
ug/mL
 4
b-NGF
 60.0 71
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 4
b-NGF
 34.0 82
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 4
b-NGF
 40.5 56
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 4
b-NGF
 46.0 62
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 4
b-NGF
 33.0 53
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 4
b-NGF
 40.0 70
RA2159 Ruxolitinib 0.3
uM
 4
b-NGF
 44.5 46
N2586 IL-6 100
ug/mL
 4
b-NGF
 98.0 57
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 4
b-NGF
 111.0 62
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 4
b-NGF
 76.0 45