Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 Leptin 1
ng/mL
 1
b-NGF
 39.0 31
RA2159 IKK16 2.0
uM
 Leptin 1
ng/mL
 1
b-NGF
 35.5 36
N2586 Leptin 1
ng/mL
 1
b-NGF
 75.0 28
N2586 PD184352 0.1
uM
 Leptin 1
ng/mL
 1
b-NGF
 85.5 40
N2586 Lestaurtinib 0.3
uM
 Leptin 1
ng/mL
 1
b-NGF
 53.0 41
N2586 Ruxolitinib 0.3
uM
 Leptin 1
ng/mL
 1
b-NGF
 72.0 25
N2586 Tofacitinib 0.3
uM
 Leptin 1
ng/mL
 1
b-NGF
 63.0 44
N2586 IKK16 2.0
uM
 Leptin 1
ng/mL
 1
b-NGF
 61.0 53
RA2159 1
b-NGF
 0
RA2159 PD184352 0.1
uM
 1
b-NGF
 0
RA2159 Lestaurtinib 0.3
uM
 1
b-NGF
 0
RA2159 Ruxolitinib 0.3
uM
 1
b-NGF
 0
RA2159 Tofacitinib 0.3
uM
 1
b-NGF
 0
RA2159 IKK16 2.0
uM
 1
b-NGF
 0
RA2159 1
b-NGF
 0
N2586 1
b-NGF
 0
N2586 PD184352 0.1
uM
 1
b-NGF
 0
N2586 Lestaurtinib 0.3
uM
 1
b-NGF
 0
N2586 Ruxolitinib 0.3
uM
 1
b-NGF
 0
N2586 Tofacitinib 0.3
uM
 1
b-NGF
 0
N2586 IKK16 2.0
uM
 1
b-NGF
 0
N2586 1
b-NGF
 0
RA2159 Visfatin 1
ng/mL
 1
b-NGF
 64.0 53
RA2159 PD184352 0.1
uM
 Visfatin 1
ng/mL
 1
b-NGF
 57.0 67
RA2159 Lestaurtinib 0.3
uM
 Visfatin 1
ng/mL
 1
b-NGF
 52.0 61