Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 JNK-IN-11 0.3
uM
 4
IL18
 15.5 24
RA2159 IKK16 2.0
uM
 4
IL18
 13.5 10
N2586 4
IL18
 61.0 9
N2586 EO1428 1.0
uM
 4
IL18
 74.0 15
N2586 PI103 0.1
uM
 4
IL18
 44.0 76
N2586 Sigma A6730 3.0
uM
 4
IL18
 58.5 60
N2586 JNK-IN-8 3.0
uM
 4
IL18
 56.5 44
N2586 JNK-IN-11 0.3
uM
 4
IL18
 42.5 66
N2586 IKK16 2.0
uM
 4
IL18
 54.0 55
RA2159 IL-17A 100
ng/mL
 4
IL18
 19.0 63
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 4
IL18
 30.0 72
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 4
IL18
 21.0 87
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 4
IL18
 24.0 85
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 4
IL18
 21.0 73
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 4
IL18
 19.0 78
RA2159 Tofacitinib 0.3
uM
 4
IL18
 23.0 33
N2586 IL-17A 100
ng/mL
 4
IL18
 73.0 61
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 4
IL18
 74.5 60
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 4
IL18
 78.0 61
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 4
IL18
 72.0 55
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 4
IL18
 57.5 68
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 4
IL18
 42.0 73
N2586 Tofacitinib 0.3
uM
 4
IL18
 31.0 65
RA2159 IL-6 100
ug/mL
 4
IL18
 31.0 85
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 4
IL18
 25.0 77