Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 4
TNFb
 36.0 50
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 4
TNFb
 30.0 46
N2586 Ruxolitinib 0.3
uM
 4
TNFb
 49.5 46
RA2159 IL-1 alpha 100
ng/mL
 4
TNFb
 73.0 74
RA2159 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 50.5 50
RA2159 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 151.0 69
RA2159 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 56.0 60
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 66.0 33
RA2159 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 96.0 39
RA2159 Lestaurtinib 0.3
uM
 4
TNFb
 39.0 71
N2586 IL-1 alpha 100
ng/mL
 4
TNFb
 60.0 39
N2586 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 52.0 64
N2586 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 64.0 49
N2586 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 97.0 65
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 50.0 53
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 74.5 62
N2586 Lestaurtinib 0.3
uM
 4
TNFb
 43.0 41
0
TNFb
 62.0 52
RA2159 TNF-a 100
ng/mL
 4
TNFb
 55.5 48
RA2159 EO1428 1.0
uM
 TNF-a 100
ng/mL
 4
TNFb
 52.0 48
RA2159 PI103 0.1
uM
 TNF-a 100
ng/mL
 4
TNFb
 39.0 41
RA2159 Sigma A6730 3.0
uM
 TNF-a 100
ng/mL
 4
TNFb
 36.0 60
RA2159 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 4
TNFb
 37.0 55
RA2159 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 4
TNFb
 43.0 67
RA2159 PD184352 0.1
uM
 4
TNFb
 33.0 35