Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
MIP-1B
 63.0 81
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
MIP-1B
 66.0 58
RA2159 Ruxolitinib 0.3
uM
 2
MIP-1B
 63.5 56
N2586 IL-6 100
ug/mL
 2
MIP-1B
 63.0 77
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
MIP-1B
 58.0 88
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 2
MIP-1B
 63.5 56
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
MIP-1B
 63.5 46
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
MIP-1B
 64.0 55
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
MIP-1B
 67.0 69
N2586 Ruxolitinib 0.3
uM
 2
MIP-1B
 63.0 64
RA2159 IL-17A 100
ng/mL
 2
MIP-1B
 69.5 56
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 70.0 75
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 68.0 75
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 68.0 73
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 68.0 61
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 64.0 67
RA2159 Tofacitinib 0.3
uM
 2
MIP-1B
 62.0 78
N2586 IL-17A 100
ng/mL
 2
MIP-1B
 70.0 55
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 66.0 50
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 65.0 57
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 70.0 75
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 66.5 52
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
MIP-1B
 72.0 69
N2586 Tofacitinib 0.3
uM
 2
MIP-1B
 69.0 45
RA2159 2
MIP-1B
 64.0 74