Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP | Mapatumumab | 25.0 | nM | anti-Fc | 25.0 | nM | 2 | -4.55 | 92.1239 | 0.381 | 0.66372 | 0.64307 | ||||||
| HeLa ICRP | Mapatumumab | 25.0 | nM | anti-Fc | 25.0 | nM | 3 | -4.54 | 92.8286 | 0.238 | 0.83860 | 0.78369 | ||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | anti-Fc | 100.0 | nM | 1 | -4.50 | 87.7636 | 0.273 | 0.80364 | 0.73091 | ||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | anti-Fc | 100.0 | nM | 2 | -4.57 | 88.4746 | 0.369 | 0.65085 | 0.66780 | ||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | anti-Fc | 100.0 | nM | 3 | -4.54 | 86.0039 | 0.218 | 0.84016 | 0.79337 | ||||||
| HeLa ICRP | Mapatumumab | 200.0 | nM | anti-Fc | 200.0 | nM | 1 | -4.52 | 86.0180 | 0.228 | 0.82635 | 0.80040 | ||||||
| HeLa ICRP | Mapatumumab | 200.0 | nM | anti-Fc | 200.0 | nM | 2 | -4.69 | 101.5925 | 0.438 | 0.79391 | 0.66979 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | 1 | -5.47 | 338.7050 | 0.034 | 0.89448 | 0.31894 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | 2 | -5.47 | 319.6967 | 0.075 | 0.86936 | 0.30949 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | anti-Fc | 10.0 | nM | 1 | -4.70 | 139.7368 | 0.011 | 0.92026 | 0.78469 | |||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | anti-Fc | 10.0 | nM | 2 | -4.93 | 186.2624 | 0.010 | 0.90759 | 0.68812 | |||
| HeLa ICRP | Apomab | 25.0 | nM | 1 | -6.44 | 211.4919 | 0.968 | 0.97581 | 0.75806 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | 2 | -6.45 | 249.8519 | 0.956 | 0.97037 | 0.88148 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | 3 | -6.37 | 263.5100 | 0.877 | 0.87966 | 0.88252 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | 4 | -6.67 | 260.1646 | 0.889 | 0.89300 | 0.83951 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | 5 | -6.58 | 309.2188 | 0.901 | 0.90865 | 0.88462 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | 6 | -6.53 | 267.1805 | 0.838 | 0.85338 | 0.84962 | |||||||||
| HeLa ICRP | Apomab | 50.0 | nM | 1 | -6.39 | 285.0388 | 0.953 | 0.95349 | 0.85271 | |||||||||
| HeLa ICRP | Apomab | 50.0 | nM | 2 | -6.48 | 250.9659 | 0.972 | 0.98864 | 0.80682 | |||||||||
| HeLa ICRP | Apomab | 100.0 | nM | 1 | -6.13 | 217.8947 | 0.934 | 0.92763 | 0.77632 | |||||||||
| HeLa ICRP | Apomab | 100.0 | nM | 2 | -6.31 | 231.7647 | 0.971 | 0.98529 | 0.85294 | |||||||||
| HeLa ICRP | Apomab | 100.0 | nM | 3 | -6.54 | 273.3562 | 0.911 | 0.95205 | 0.84932 | |||||||||
| HeLa ICRP | Apomab | 200.0 | nM | 1 | -6.25 | 250.2333 | 0.940 | 0.96667 | 0.85333 | |||||||||
| HeLa ICRP | Apomab | 200.0 | nM | 2 | -6.34 | 213.4375 | 0.929 | 0.94643 | 0.78571 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | anti-Fc | 25.0 | nM | 1 | -5.57 | 236.0268 | 0.848 | 0.90179 | 0.77679 |