PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
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| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| WM1552C | 1 | hr | p-S6(S235/236) | 1.66360 | -0.46491 |
| WM1552C | 1 | hr | p-p70S6K(T389) | 3.53240 | -1.46320 |
| WM1552C | 1 | hr | p-p70S6K(T421/S424) | 3.73010 | -1.50190 |
| WM1552C | 1 | hr | p-mTOR(S2448) | 3.76830 | -1.23060 |
| WM1552C | 1 | hr | p-AKT(S473) | 1.14920 | -1.09220 |
| WM1552C | avg(48,72) | hr | Viability | 4.53630 | 2.24070 |
| WM1552C | 1 | hr | p-AKT(T308) | 1.88800 | -1.58740 |
| WM1552C | 1 | hr | p-p90RSK(T573) | 2.88470 | -0.62720 |
| WM1552C | 1 | hr | p-p90RSK(S380) | 3.28960 | -1.18130 |
| WM1552C | 1 | hr | p-AMPK(T172) | 3.88070 | -1.32480 |