PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| MZ7-mel | 5 | hr | p-HSP27(S82) | -3.05540 | -2.49330 |
| WM1552C | 10 | hr | p-AKT(S473) | 0.07012 | -2.47900 |
| MZ7-mel | 5 | hr | p-cJun(S63) | -3.66140 | -2.47590 |
| COLO 858 | 10 | hr | p-HSP27(S82) | 0.42086 | -2.47090 |
| MZ7-mel | 5 | hr | p-mTOR(S2448) | -2.49350 | -2.33630 |
| MZ7-mel | 5 | hr | p-AKT(S473) | -2.74790 | -2.30700 |
| RVH-421 | 48 | hr | p-AMPK(T172) | -0.11719 | -2.28580 |
| RVH-421 | 1 | hr | p-AMPK(T172) | 4.14660 | -2.28560 |
| C32 | 48 | hr | cPARP | -9.15590 | -2.27710 |
| WM1552C | 10 | hr | p-p70S6K(T389) | 2.36010 | -2.27460 |
| WM1552C | 10 | hr | p-p90RSK(S380) | 2.09060 | -2.26740 |
| COLO 858 | 48 | hr | p-p90RSK(S380) | 4.48040 | -2.25410 |
| MZ7-mel | 5 | hr | p-p70S6K(T421/S424) | -1.74550 | -2.24660 |
| RVH-421 | 1 | hr | p27 Kip1 | 3.29140 | -2.22920 |
| RVH-421 | 1 | hr | p-Histone H3(S10) | 2.63930 | -2.21930 |
| MZ7-mel | 5 | hr | Bim | -3.65960 | -2.19740 |
| SKMEL28 | 10 | hr | p-AKT(S473) | 2.22460 | -2.17770 |
| MMAC-SF | 24 | hr | p27 Kip1 | -8.74820 | -2.17230 |
| WM1552C | 10 | hr | p-p70S6K(T421/S424) | 2.31340 | -2.16600 |
| MZ7-mel | 5 | hr | p-p90RSK(T573) | -2.90740 | -2.16400 |
| COLO 858 | 24 | hr | p-HSP27(S82) | -1.41810 | -2.15680 |
| COLO 858 | 48 | hr | p-p90RSK(T573) | 4.71400 | -2.15680 |
| RVH-421 | 1 | hr | p-NFKB(S536) | 3.91770 | -2.15360 |
| MMAC-SF | 48 | hr | p-p90RSK(S380) | 5.05320 | -2.13280 |
| RVH-421 | 48 | hr | Bim | -2.95910 | -2.12480 |