Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
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| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | LOXIMVI | 5.0000 | uM | 24 | hr | | Ki-67 | 2047.60 | p-Rb(S807/S811) | 78.14 | p-cJun(S73) | 80.02 | 1 | LOXIMVI-signal3 | B2 | |
| JNK-IN-8 | LOXIMVI | 0.8000 | uM | 24 | hr | | Ki-67 | 3017.80 | p-Rb(S807/S811) | 223.34 | p-cJun(S73) | 56.18 | 2 | LOXIMVI-signal3 | E4 | |
| Vemurafenib | LOXIMVI | 0.0033 | uM | 24 | hr | | Ki-67 | 2929.90 | p-Rb(S807/S811) | 202.41 | p-cJun(S73) | 113.58 | 1 | LOXIMVI-signal3 | B10 | |
| JNK-IN-8 | LOXIMVI | 2.0000 | uM | 24 | hr | | Ki-67 | 3091.80 | p-Rb(S807/S811) | 251.41 | p-cJun(S73) | 53.20 | 2 | LOXIMVI-signal3 | E3 | |
| JNK-IN-8 | LOXIMVI | 0.0033 | uM | 24 | hr | | Ki-67 | 2844.80 | p-Rb(S807/S811) | 201.31 | p-cJun(S73) | 107.70 | 1 | LOXIMVI-signal3 | D10 | |
| JNK-IN-8 | LOXIMVI | 0.3200 | uM | 24 | hr | | Ki-67 | 2939.70 | p-Rb(S807/S811) | 217.05 | p-cJun(S73) | 57.83 | 1 | LOXIMVI-signal3 | D5 | |
| JNK-IN-8 | LOXIMVI | 0.1280 | uM | 24 | hr | | Ki-67 | 2922.80 | p-Rb(S807/S811) | 202.58 | p-cJun(S73) | 68.33 | 1 | LOXIMVI-signal3 | D6 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2882.90 | p-Rb(S807/S811) | 203.40 | p-cJun(S73) | 97.65 | 1 | LOXIMVI-signal3 | F10 |
| Vemurafenib | LOXIMVI | 5.0000 | uM | 24 | hr | | Ki-67 | 1979.00 | p-Rb(S807/S811) | 73.51 | p-cJun(S73) | 77.14 | 2 | LOXIMVI-signal3 | C2 | |
| JNK-IN-8 | LOXIMVI | 2.0000 | uM | 24 | hr | | Ki-67 | 3123.80 | p-Rb(S807/S811) | 257.55 | p-cJun(S73) | 54.72 | 1 | LOXIMVI-signal3 | D3 | |
| Vemurafenib | LOXIMVI | 0.3200 | uM | 24 | hr | | Ki-67 | 2470.00 | p-Rb(S807/S811) | 138.22 | p-cJun(S73) | 75.91 | 1 | LOXIMVI-signal3 | B5 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 3032.30 | p-Rb(S807/S811) | 209.50 | p-cJun(S73) | 127.94 | 1 | LOXIMVI-signal3 | F11 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2829.00 | p-Rb(S807/S811) | 197.37 | p-cJun(S73) | 98.13 | 2 | LOXIMVI-signal3 | G10 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.8000 | uM | 24 | hr | | Ki-67 | 2219.70 | p-Rb(S807/S811) | 100.07 | p-cJun(S73) | 23.48 | 2 | LOXIMVI-signal3 | G4 |
| JNK-IN-8 | LOXIMVI | 0.0000 | uM | 24 | hr | | Ki-67 | 3030.30 | p-Rb(S807/S811) | 205.20 | p-cJun(S73) | 122.59 | 2 | LOXIMVI-signal3 | E11 | |
| Vemurafenib | LOXIMVI | 2.0000 | uM | 24 | hr | | Ki-67 | 2153.30 | p-Rb(S807/S811) | 92.72 | p-cJun(S73) | 84.91 | 2 | LOXIMVI-signal3 | C3 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 2934.10 | p-Rb(S807/S811) | 203.26 | p-cJun(S73) | 120.51 | 2 | LOXIMVI-signal3 | G11 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 2814.00 | p-Rb(S807/S811) | 96.96 | p-cJun(S73) | 30.63 | 1 | LOXIMVI-signal3 | F2 |
| JNK-IN-8 | LOXIMVI | 0.1280 | uM | 24 | hr | | Ki-67 | 2886.70 | p-Rb(S807/S811) | 203.46 | p-cJun(S73) | 63.66 | 2 | LOXIMVI-signal3 | E6 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 2767.00 | p-Rb(S807/S811) | 114.93 | p-cJun(S73) | 35.58 | 2 | LOXIMVI-signal3 | G2 |
| JNK-IN-8 | LOXIMVI | 5.0000 | uM | 24 | hr | | Ki-67 | 3004.40 | p-Rb(S807/S811) | 244.06 | p-cJun(S73) | 51.77 | 1 | LOXIMVI-signal3 | D2 | |
| JNK-IN-8 | LOXIMVI | 0.3200 | uM | 24 | hr | | Ki-67 | 2848.50 | p-Rb(S807/S811) | 207.66 | p-cJun(S73) | 57.32 | 2 | LOXIMVI-signal3 | E5 | |
| JNK-IN-8 | LOXIMVI | 5.0000 | uM | 24 | hr | | Ki-67 | 2973.70 | p-Rb(S807/S811) | 240.23 | p-cJun(S73) | 48.04 | 2 | LOXIMVI-signal3 | E2 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.8000 | uM | 24 | hr | | Ki-67 | 2249.30 | p-Rb(S807/S811) | 93.65 | p-cJun(S73) | 24.47 | 1 | LOXIMVI-signal3 | F4 |
| JNK-IN-8 | LOXIMVI | 0.8000 | uM | 24 | hr | | Ki-67 | 2971.40 | p-Rb(S807/S811) | 219.05 | p-cJun(S73) | 57.05 | 1 | LOXIMVI-signal3 | D4 |