Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
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| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | WM-115 | JNK-IN-8 | 2.0000 | uM | 24 | hr | | Ki-67 | 684.33 | p-Rb(S807/S811) | 51.01 | p-cJun(S73) | 18.52 | 1 | WM115-signal3 | F3 |
| JNK-IN-8 | WM-115 | 0.3200 | uM | 24 | hr | | Ki-67 | 814.81 | p-Rb(S807/S811) | 81.21 | p-cJun(S73) | 22.95 | 1 | WM115-signal3 | D5 | |
| Vemurafenib | WM-115 | 0.0000 | uM | 24 | hr | | Ki-67 | 738.43 | p-Rb(S807/S811) | 73.77 | p-cJun(S73) | 49.75 | 1 | WM115-signal3 | B11 | |
| Vemurafenib | WM-115 | 0.0205 | uM | 24 | hr | | Ki-67 | 780.78 | p-Rb(S807/S811) | 72.14 | p-cJun(S73) | 50.93 | 1 | WM115-signal3 | B8 | |
| Vemurafenib | WM-115 | JNK-IN-8 | 0.3200 | uM | 24 | hr | | Ki-67 | 737.49 | p-Rb(S807/S811) | 41.43 | p-cJun(S73) | 27.30 | 1 | WM115-signal3 | F5 |
| Vemurafenib | WM-115 | 5.0000 | uM | 24 | hr | | Ki-67 | 635.32 | p-Rb(S807/S811) | 49.14 | p-cJun(S73) | 49.50 | 2 | WM115-signal3 | C2 | |
| JNK-IN-8 | WM-115 | 5.0000 | uM | 24 | hr | | Ki-67 | 808.69 | p-Rb(S807/S811) | 76.27 | p-cJun(S73) | 22.54 | 2 | WM115-signal3 | E2 | |
| Vemurafenib | WM-115 | 0.1280 | uM | 24 | hr | | Ki-67 | 784.48 | p-Rb(S807/S811) | 55.88 | p-cJun(S73) | 67.92 | 1 | WM115-signal3 | B6 | |
| JNK-IN-8 | WM-115 | 0.0033 | uM | 24 | hr | | Ki-67 | 783.34 | p-Rb(S807/S811) | 75.14 | p-cJun(S73) | 46.08 | 1 | WM115-signal3 | D10 | |
| Vemurafenib | WM-115 | 0.3200 | uM | 24 | hr | | Ki-67 | 587.55 | p-Rb(S807/S811) | 26.27 | p-cJun(S73) | 71.93 | 2 | WM115-signal3 | C5 | |
| Vemurafenib | WM-115 | 0.0000 | uM | 24 | hr | | Ki-67 | 699.08 | p-Rb(S807/S811) | 74.05 | p-cJun(S73) | 48.96 | 2 | WM115-signal3 | C11 | |
| Vemurafenib | WM-115 | 0.0033 | uM | 24 | hr | | Ki-67 | 706.27 | p-Rb(S807/S811) | 71.35 | p-cJun(S73) | 46.99 | 2 | WM115-signal3 | C10 | |
| Vemurafenib | WM-115 | 2.0000 | uM | 24 | hr | | Ki-67 | 671.20 | p-Rb(S807/S811) | 44.63 | p-cJun(S73) | 68.10 | 1 | WM115-signal3 | B3 | |
| JNK-IN-8 | WM-115 | 2.0000 | uM | 24 | hr | | Ki-67 | 815.32 | p-Rb(S807/S811) | 84.33 | p-cJun(S73) | 22.27 | 2 | WM115-signal3 | E3 | |
| Vemurafenib | WM-115 | JNK-IN-8 | 0.1280 | uM | 24 | hr | | Ki-67 | 783.22 | p-Rb(S807/S811) | 57.39 | p-cJun(S73) | 35.93 | 1 | WM115-signal3 | F6 |
| JNK-IN-8 | WM-115 | 0.0205 | uM | 24 | hr | | Ki-67 | 798.51 | p-Rb(S807/S811) | 76.68 | p-cJun(S73) | 41.54 | 2 | WM115-signal3 | E8 | |
| JNK-IN-8 | WM-115 | 0.0082 | uM | 24 | hr | | Ki-67 | 787.98 | p-Rb(S807/S811) | 73.62 | p-cJun(S73) | 42.75 | 2 | WM115-signal3 | E9 | |
| JNK-IN-8 | WM-115 | 0.0033 | uM | 24 | hr | | Ki-67 | 740.57 | p-Rb(S807/S811) | 72.45 | p-cJun(S73) | 46.35 | 2 | WM115-signal3 | E10 | |
| Vemurafenib | WM-115 | 0.0082 | uM | 24 | hr | | Ki-67 | 788.63 | p-Rb(S807/S811) | 73.58 | p-cJun(S73) | 49.70 | 1 | WM115-signal3 | B9 | |
| Vemurafenib | WM-115 | JNK-IN-8 | 0.3200 | uM | 24 | hr | | Ki-67 | 738.56 | p-Rb(S807/S811) | 42.13 | p-cJun(S73) | 27.75 | 2 | WM115-signal3 | G5 |
| JNK-IN-8 | WM-115 | 0.8000 | uM | 24 | hr | | Ki-67 | 812.54 | p-Rb(S807/S811) | 82.01 | p-cJun(S73) | 21.32 | 1 | WM115-signal3 | D4 | |
| Vemurafenib | WM-115 | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 801.31 | p-Rb(S807/S811) | 74.66 | p-cJun(S73) | 48.32 | 1 | WM115-signal3 | F10 |
| Vemurafenib | WM-115 | JNK-IN-8 | 0.0512 | uM | 24 | hr | | Ki-67 | 764.21 | p-Rb(S807/S811) | 71.74 | p-cJun(S73) | 39.60 | 2 | WM115-signal3 | G7 |
| JNK-IN-8 | WM-115 | 5.0000 | uM | 24 | hr | | Ki-67 | 867.38 | p-Rb(S807/S811) | 85.79 | p-cJun(S73) | 23.05 | 1 | WM115-signal3 | D2 | |
| Vemurafenib | WM-115 | JNK-IN-8 | 0.1280 | uM | 24 | hr | | Ki-67 | 779.71 | p-Rb(S807/S811) | 58.29 | p-cJun(S73) | 34.35 | 2 | WM115-signal3 | G6 |