Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | WM-115 | 0.0032 | uM | 24 | hr | 533 | 33 | 0.9549 | 1.1746 | 0.0619 | 0.0555 | 3 |
| Vemurafenib | WM-115 | 0.0032 | uM | 24 | hr | 748 | 48 | 1.3369 | 1.1746 | 0.0642 | 0.0555 | 4 |
| Vemurafenib | WM-115 | 0.0032 | uM | 48 | hr | 792 | 46 | 1.5061 | 1.0448 | 0.0581 | 0.0621 | 1 |
| Vemurafenib | WM-115 | 0.0032 | uM | 48 | hr | 731 | 37 | 1.4011 | 1.0448 | 0.0506 | 0.0621 | 2 |
| Vemurafenib | WM-115 | 0.0032 | uM | 48 | hr | 398 | 27 | 0.7490 | 1.0448 | 0.0678 | 0.0621 | 3 |
| Vemurafenib | WM-115 | 0.0032 | uM | 48 | hr | 279 | 20 | 0.5229 | 1.0448 | 0.0717 | 0.0621 | 4 |
| Vemurafenib | WM-115 | 0.0032 | uM | 72 | hr | 2999 | 81 | 0.9626 | 0.9531 | 0.0270 | 0.0323 | 1 |
| Vemurafenib | WM-115 | 0.0032 | uM | 72 | hr | 2706 | 89 | 0.8633 | 0.9531 | 0.0329 | 0.0323 | 2 |
| Vemurafenib | WM-115 | 0.0032 | uM | 72 | hr | 3192 | 119 | 1.0137 | 0.9531 | 0.0373 | 0.0323 | 3 |
| Vemurafenib | WM-115 | 0.0032 | uM | 72 | hr | 3047 | 98 | 0.9728 | 0.9531 | 0.0322 | 0.0323 | 4 |
| Vemurafenib | WM-115 | 0.0100 | uM | 24 | hr | 498 | 24 | 0.9053 | 1.2046 | 0.0482 | 0.0451 | 1 |
| Vemurafenib | WM-115 | 0.0100 | uM | 24 | hr | 670 | 16 | 1.2490 | 1.2046 | 0.0239 | 0.0451 | 2 |
| Vemurafenib | WM-115 | 0.0100 | uM | 24 | hr | 662 | 40 | 1.1879 | 1.2046 | 0.0604 | 0.0451 | 3 |
| Vemurafenib | WM-115 | 0.0100 | uM | 24 | hr | 812 | 39 | 1.4763 | 1.2046 | 0.0480 | 0.0451 | 4 |
| Vemurafenib | WM-115 | 0.0100 | uM | 48 | hr | 780 | 26 | 1.5222 | 1.2411 | 0.0333 | 0.0504 | 1 |
| Vemurafenib | WM-115 | 0.0100 | uM | 48 | hr | 928 | 38 | 1.7968 | 1.2411 | 0.0409 | 0.0504 | 2 |
| Vemurafenib | WM-115 | 0.0100 | uM | 48 | hr | 373 | 25 | 0.7026 | 1.2411 | 0.0670 | 0.0504 | 3 |
| Vemurafenib | WM-115 | 0.0100 | uM | 48 | hr | 497 | 30 | 0.9428 | 1.2411 | 0.0604 | 0.0504 | 4 |
| Vemurafenib | WM-115 | 0.0100 | uM | 72 | hr | 3094 | 104 | 0.9863 | 1.0364 | 0.0336 | 0.0325 | 1 |
| Vemurafenib | WM-115 | 0.0100 | uM | 72 | hr | 3201 | 85 | 1.0279 | 1.0364 | 0.0266 | 0.0325 | 2 |
| Vemurafenib | WM-115 | 0.0100 | uM | 72 | hr | 3315 | 107 | 1.0582 | 1.0364 | 0.0323 | 0.0325 | 3 |
| Vemurafenib | WM-115 | 0.0100 | uM | 72 | hr | 3380 | 127 | 1.0731 | 1.0364 | 0.0376 | 0.0325 | 4 |
| Vemurafenib | WM-115 | 0.0316 | uM | 24 | hr | 606 | 46 | 1.0695 | 1.2214 | 0.0759 | 0.0561 | 1 |
| Vemurafenib | WM-115 | 0.0316 | uM | 24 | hr | 538 | 26 | 0.9779 | 1.2214 | 0.0483 | 0.0561 | 2 |
| Vemurafenib | WM-115 | 0.0316 | uM | 24 | hr | 615 | 26 | 1.1249 | 1.2214 | 0.0423 | 0.0561 | 3 |