Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | WM-115 | 0.1000 | uM | 24 | hr | 651 | 26 | 1.1937 | 1.2715 | 0.0399 | 0.0423 | 1 |
| Selumetinib | WM-115 | 0.1000 | uM | 24 | hr | 472 | 23 | 0.8575 | 1.2715 | 0.0487 | 0.0423 | 2 |
| Selumetinib | WM-115 | 0.1000 | uM | 24 | hr | 944 | 43 | 1.7208 | 1.2715 | 0.0456 | 0.0423 | 3 |
| Selumetinib | WM-115 | 0.1000 | uM | 24 | hr | 713 | 25 | 1.3140 | 1.2715 | 0.0351 | 0.0423 | 4 |
| Selumetinib | WM-115 | 0.1000 | uM | 48 | hr | 930 | 35 | 1.8069 | 1.4793 | 0.0376 | 0.0394 | 1 |
| Selumetinib | WM-115 | 0.1000 | uM | 48 | hr | 975 | 39 | 1.8897 | 1.4793 | 0.0400 | 0.0394 | 2 |
| Selumetinib | WM-115 | 0.1000 | uM | 48 | hr | 602 | 25 | 1.1649 | 1.4793 | 0.0415 | 0.0394 | 3 |
| Selumetinib | WM-115 | 0.1000 | uM | 48 | hr | 544 | 21 | 1.0559 | 1.4793 | 0.0386 | 0.0394 | 4 |
| Selumetinib | WM-115 | 0.1000 | uM | 72 | hr | 2126 | 130 | 0.6584 | 0.7512 | 0.0611 | 0.0559 | 1 |
| Selumetinib | WM-115 | 0.1000 | uM | 72 | hr | 2388 | 128 | 0.7455 | 0.7512 | 0.0536 | 0.0559 | 2 |
| Selumetinib | WM-115 | 0.1000 | uM | 72 | hr | 2594 | 122 | 0.8154 | 0.7512 | 0.0470 | 0.0559 | 3 |
| Selumetinib | WM-115 | 0.1000 | uM | 72 | hr | 2538 | 157 | 0.7854 | 0.7512 | 0.0619 | 0.0559 | 4 |
| Selumetinib | WM-115 | 0.3160 | uM | 24 | hr | 628 | 32 | 1.1383 | 1.4625 | 0.0510 | 0.0578 | 1 |
| Selumetinib | WM-115 | 0.3160 | uM | 24 | hr | 737 | 53 | 1.3063 | 1.4625 | 0.0719 | 0.0578 | 2 |
| Selumetinib | WM-115 | 0.3160 | uM | 24 | hr | 941 | 44 | 1.7131 | 1.4625 | 0.0468 | 0.0578 | 3 |
| Selumetinib | WM-115 | 0.3160 | uM | 24 | hr | 944 | 58 | 1.6921 | 1.4625 | 0.0614 | 0.0578 | 4 |
| Selumetinib | WM-115 | 0.3160 | uM | 48 | hr | 763 | 54 | 1.4314 | 1.2396 | 0.0708 | 0.0720 | 1 |
| Selumetinib | WM-115 | 0.3160 | uM | 48 | hr | 847 | 44 | 1.6212 | 1.2396 | 0.0519 | 0.0720 | 2 |
| Selumetinib | WM-115 | 0.3160 | uM | 48 | hr | 515 | 44 | 0.9509 | 1.2396 | 0.0854 | 0.0720 | 3 |
| Selumetinib | WM-115 | 0.3160 | uM | 48 | hr | 514 | 41 | 0.9549 | 1.2396 | 0.0798 | 0.0720 | 4 |
| Selumetinib | WM-115 | 0.3160 | uM | 72 | hr | 1786 | 228 | 0.5139 | 0.5866 | 0.1277 | 0.1146 | 1 |
| Selumetinib | WM-115 | 0.3160 | uM | 72 | hr | 1951 | 241 | 0.5641 | 0.5866 | 0.1235 | 0.1146 | 2 |
| Selumetinib | WM-115 | 0.3160 | uM | 72 | hr | 2127 | 217 | 0.6300 | 0.5866 | 0.1020 | 0.1146 | 3 |
| Selumetinib | WM-115 | 0.3160 | uM | 72 | hr | 2162 | 227 | 0.6383 | 0.5866 | 0.1050 | 0.1146 | 4 |
| Selumetinib | WM-115 | 1.0000 | uM | 24 | hr | 485 | 46 | 0.8384 | 0.8900 | 0.0948 | 0.1020 | 1 |