Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | COLO 858 | 0.1000 | uM | 24 | hr | 4580 | 239 | 1.4501 | 1.1715 | 0.0522 | 0.0482 | 2 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 24 | hr | 2766 | 129 | 0.8809 | 1.1715 | 0.0466 | 0.0482 | 3 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 24 | hr | 2705 | 111 | 0.8665 | 1.1715 | 0.0410 | 0.0482 | 4 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 48 | hr | 3788 | 184 | 0.8235 | 0.8929 | 0.0486 | 0.0498 | 1 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 48 | hr | 3921 | 213 | 0.8472 | 0.8929 | 0.0543 | 0.0498 | 2 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 48 | hr | 4378 | 206 | 0.9532 | 0.8929 | 0.0471 | 0.0498 | 3 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 48 | hr | 4361 | 214 | 0.9475 | 0.8929 | 0.0491 | 0.0498 | 4 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 72 | hr | 2562 | 140 | 0.8798 | 0.8933 | 0.0546 | 0.0530 | 1 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 72 | hr | 2228 | 126 | 0.7635 | 0.8933 | 0.0566 | 0.0530 | 2 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 72 | hr | 2653 | 147 | 0.9103 | 0.8933 | 0.0554 | 0.0530 | 3 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 72 | hr | 2940 | 133 | 1.0196 | 0.8933 | 0.0452 | 0.0530 | 4 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 24 | hr | 3986 | 218 | 1.2586 | 1.0207 | 0.0547 | 0.0562 | 1 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 24 | hr | 4223 | 244 | 1.3291 | 1.0207 | 0.0578 | 0.0562 | 2 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 24 | hr | 2498 | 145 | 0.7860 | 1.0207 | 0.0580 | 0.0562 | 3 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 24 | hr | 2245 | 122 | 0.7092 | 1.0207 | 0.0543 | 0.0562 | 4 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 48 | hr | 2481 | 202 | 0.5207 | 0.5381 | 0.0814 | 0.0785 | 1 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 48 | hr | 2718 | 200 | 0.5753 | 0.5381 | 0.0736 | 0.0785 | 2 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 48 | hr | 2572 | 202 | 0.5415 | 0.5381 | 0.0785 | 0.0785 | 3 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 48 | hr | 2450 | 197 | 0.5148 | 0.5381 | 0.0804 | 0.0785 | 4 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 72 | hr | 1548 | 140 | 0.5114 | 0.5691 | 0.0904 | 0.0842 | 1 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 72 | hr | 1481 | 147 | 0.4846 | 0.5691 | 0.0993 | 0.0842 | 2 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 72 | hr | 1936 | 144 | 0.6509 | 0.5691 | 0.0744 | 0.0842 | 3 |
| PLX-4720 | COLO 858 | 0.3160 | uM | 72 | hr | 1869 | 136 | 0.6295 | 0.5691 | 0.0728 | 0.0842 | 4 |
| PLX-4720 | COLO 858 | 1.0000 | uM | 24 | hr | 4055 | 427 | 1.2119 | 0.9459 | 0.1053 | 0.1081 | 1 |
| PLX-4720 | COLO 858 | 1.0000 | uM | 24 | hr | 3930 | 382 | 1.1852 | 0.9459 | 0.0972 | 0.1081 | 2 |