Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 WM1552C 3.1600
uM
 24
hr
 4
PLX-4720 WM1552C 3.1600
uM
 48
hr
 2513 148 0.7523 0.7234 0.0589 0.0762 1
PLX-4720 WM1552C 3.1600
uM
 48
hr
 2469 143 0.7399 0.7234 0.0579 0.0762 2
PLX-4720 WM1552C 3.1600
uM
 48
hr
 2431 242 0.6963 0.7234 0.0995 0.0762 3
PLX-4720 WM1552C 3.1600
uM
 48
hr
 2432 215 0.7052 0.7234 0.0884 0.0762 4
PLX-4720 WM1552C 3.1600
uM
 72
hr
 3305 420 0.5596 0.4966 0.1271 0.1295 1
PLX-4720 WM1552C 3.1600
uM
 72
hr
 3028 426 0.5047 0.4966 0.1407 0.1295 2
PLX-4720 WM1552C 3.1600
uM
 72
hr
 2644 325 0.4498 0.4966 0.1229 0.1295 3
PLX-4720 WM1552C 3.1600
uM
 72
hr
 2791 355 0.4725 0.4966 0.1272 0.1295 4
AZ-628 WM1552C 0.0032
uM
 24
hr
 2529 153 0.9483 0.9587 0.0605 0.0672 1
AZ-628 WM1552C 0.0032
uM
 24
hr
 2622 194 0.9691 0.9587 0.0740 0.0672 2
AZ-628 WM1552C 0.0032
uM
 24
hr
 3
AZ-628 WM1552C 0.0032
uM
 24
hr
 4
AZ-628 WM1552C 0.0032
uM
 48
hr
 3355 202 1.0030 1.0066 0.0602 0.0725 1
AZ-628 WM1552C 0.0032
uM
 48
hr
 3333 213 0.9925 1.0066 0.0639 0.0725 2
AZ-628 WM1552C 0.0032
uM
 48
hr
 3510 270 1.0306 1.0066 0.0769 0.0725 3
AZ-628 WM1552C 0.0032
uM
 48
hr
 3451 307 1.0001 1.0066 0.0890 0.0725 4
AZ-628 WM1552C 0.0032
uM
 72
hr
 5661 488 1.0034 1.0298 0.0862 0.0855 1
AZ-628 WM1552C 0.0032
uM
 72
hr
 6264 506 1.1168 1.0298 0.0808 0.0855 2
AZ-628 WM1552C 0.0032
uM
 72
hr
 5699 483 1.0117 1.0298 0.0848 0.0855 3
AZ-628 WM1552C 0.0032
uM
 72
hr
 5596 506 0.9873 1.0298 0.0904 0.0855 4
AZ-628 WM1552C 0.0100
uM
 24
hr
 2698 204 0.9954 0.9816 0.0756 0.0724 1
AZ-628 WM1552C 0.0100
uM
 24
hr
 2605 180 0.9679 0.9816 0.0691 0.0724 2
AZ-628 WM1552C 0.0100
uM
 24
hr
 3
AZ-628 WM1552C 0.0100
uM
 24
hr
 4