Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 WM1552C 0.3160
uM
 24
hr
 3
PLX-4720 WM1552C 0.3160
uM
 24
hr
 4
PLX-4720 WM1552C 0.3160
uM
 48
hr
 3087 136 0.9387 0.8386 0.0441 0.0440 1
PLX-4720 WM1552C 0.3160
uM
 48
hr
 3142 152 0.9511 0.8386 0.0484 0.0440 2
PLX-4720 WM1552C 0.3160
uM
 48
hr
 2796 178 0.8328 0.8386 0.0637 0.0440 3
PLX-4720 WM1552C 0.3160
uM
 48
hr
 2026 40 0.6318 0.8386 0.0197 0.0440 4
PLX-4720 WM1552C 0.3160
uM
 72
hr
 5248 334 0.9531 0.8305 0.0636 0.0671 1
PLX-4720 WM1552C 0.3160
uM
 72
hr
 4730 299 0.8595 0.8305 0.0632 0.0671 2
PLX-4720 WM1552C 0.3160
uM
 72
hr
 4142 302 0.7448 0.8305 0.0729 0.0671 3
PLX-4720 WM1552C 0.3160
uM
 72
hr
 4231 290 0.7644 0.8305 0.0685 0.0671 4
PLX-4720 WM1552C 1.0000
uM
 24
hr
 2884 225 1.0613 1.0644 0.0780 0.0756 1
PLX-4720 WM1552C 1.0000
uM
 24
hr
 2886 211 1.0676 1.0644 0.0731 0.0756 2
PLX-4720 WM1552C 1.0000
uM
 24
hr
 3
PLX-4720 WM1552C 1.0000
uM
 24
hr
 4
PLX-4720 WM1552C 1.0000
uM
 48
hr
 2674 123 0.8115 0.7954 0.0460 0.0563 1
PLX-4720 WM1552C 1.0000
uM
 48
hr
 2701 126 0.8191 0.7954 0.0466 0.0563 2
PLX-4720 WM1552C 1.0000
uM
 48
hr
 2873 221 0.8436 0.7954 0.0769 0.0563 3
PLX-4720 WM1552C 1.0000
uM
 48
hr
 2355 131 0.7075 0.7954 0.0556 0.0563 4
PLX-4720 WM1552C 1.0000
uM
 72
hr
 3549 333 0.6238 0.5758 0.0938 0.0953 1
PLX-4720 WM1552C 1.0000
uM
 72
hr
 3500 329 0.6151 0.5758 0.0940 0.0953 2
PLX-4720 WM1552C 1.0000
uM
 72
hr
 2937 271 0.5171 0.5758 0.0923 0.0953 3
PLX-4720 WM1552C 1.0000
uM
 72
hr
 3138 317 0.5472 0.5758 0.1010 0.0953 4
PLX-4720 WM1552C 3.1600
uM
 24
hr
 2708 215 0.9950 0.9942 0.0794 0.0738 1
PLX-4720 WM1552C 3.1600
uM
 24
hr
 2671 182 0.9934 0.9942 0.0681 0.0738 2
PLX-4720 WM1552C 3.1600
uM
 24
hr
 3