Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 SKMEL28 3.1600
uM
 72
hr
 528 56 0.3541 0.3891 0.1061 0.1047 1
PLX-4720 SKMEL28 3.1600
uM
 72
hr
 547 61 0.3646 0.3891 0.1115 0.1047 2
PLX-4720 SKMEL28 3.1600
uM
 72
hr
 625 65 0.4201 0.3891 0.1040 0.1047 3
PLX-4720 SKMEL28 3.1600
uM
 72
hr
 617 60 0.4178 0.3891 0.0972 0.1047 4
AZ-628 SKMEL28 0.0032
uM
 24
hr
 1
AZ-628 SKMEL28 0.0032
uM
 24
hr
 2
AZ-628 SKMEL28 0.0032
uM
 24
hr
 3
AZ-628 SKMEL28 0.0032
uM
 24
hr
 4
AZ-628 SKMEL28 0.0032
uM
 48
hr
 1315 46 0.7558 0.8791 0.0350 0.0400 1
AZ-628 SKMEL28 0.0032
uM
 48
hr
 1360 72 0.7671 0.8791 0.0529 0.0400 2
AZ-628 SKMEL28 0.0032
uM
 48
hr
 1722 60 0.9899 0.8791 0.0348 0.0400 3
AZ-628 SKMEL28 0.0032
uM
 48
hr
 1750 65 1.0036 0.8791 0.0371 0.0400 4
AZ-628 SKMEL28 0.0032
uM
 72
hr
 1645 52 1.1949 1.1331 0.0316 0.0319 1
AZ-628 SKMEL28 0.0032
uM
 72
hr
 1538 52 1.1147 1.1331 0.0338 0.0319 2
AZ-628 SKMEL28 0.0032
uM
 72
hr
 1405 50 1.0164 1.1331 0.0356 0.0319 3
AZ-628 SKMEL28 0.0032
uM
 72
hr
 1652 44 1.2062 1.1331 0.0266 0.0319 4
AZ-628 SKMEL28 0.0100
uM
 24
hr
 1
AZ-628 SKMEL28 0.0100
uM
 24
hr
 2
AZ-628 SKMEL28 0.0100
uM
 24
hr
 3
AZ-628 SKMEL28 0.0100
uM
 24
hr
 4
AZ-628 SKMEL28 0.0100
uM
 48
hr
 2535 86 1.4586 1.4031 0.0339 0.0326 1
AZ-628 SKMEL28 0.0100
uM
 48
hr
 2367 92 1.3550 1.4031 0.0389 0.0326 2
AZ-628 SKMEL28 0.0100
uM
 48
hr
 2440 81 1.4050 1.4031 0.0332 0.0326 3
AZ-628 SKMEL28 0.0100
uM
 48
hr
 2399 59 1.3937 1.4031 0.0246 0.0326 4
AZ-628 SKMEL28 0.0100
uM
 72
hr
 1351 33 0.9887 1.0110 0.0244 0.0280 1