Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 SKMEL28 0.3160
uM
 48
hr
 1807 64 1.0381 1.1229 0.0354 0.0365 4
PLX-4720 SKMEL28 0.3160
uM
 72
hr
 760 24 0.5521 0.5984 0.0316 0.0373 1
PLX-4720 SKMEL28 0.3160
uM
 72
hr
 798 35 0.5723 0.5984 0.0439 0.0373 2
PLX-4720 SKMEL28 0.3160
uM
 72
hr
 859 28 0.6234 0.5984 0.0326 0.0373 3
PLX-4720 SKMEL28 0.3160
uM
 72
hr
 898 37 0.6459 0.5984 0.0412 0.0373 4
PLX-4720 SKMEL28 1.0000
uM
 24
hr
 1
PLX-4720 SKMEL28 1.0000
uM
 24
hr
 2
PLX-4720 SKMEL28 1.0000
uM
 24
hr
 3
PLX-4720 SKMEL28 1.0000
uM
 24
hr
 4
PLX-4720 SKMEL28 1.0000
uM
 48
hr
 1675 60 0.9619 0.9408 0.0358 0.0401 1
PLX-4720 SKMEL28 1.0000
uM
 48
hr
 1624 62 0.9303 0.9408 0.0382 0.0401 2
PLX-4720 SKMEL28 1.0000
uM
 48
hr
 1628 66 0.9303 0.9408 0.0405 0.0401 3
PLX-4720 SKMEL28 1.0000
uM
 48
hr
 1655 76 0.9405 0.9408 0.0459 0.0401 4
PLX-4720 SKMEL28 1.0000
uM
 72
hr
 579 21 0.4186 0.4583 0.0363 0.0372 1
PLX-4720 SKMEL28 1.0000
uM
 72
hr
 613 25 0.4411 0.4583 0.0408 0.0372 2
PLX-4720 SKMEL28 1.0000
uM
 72
hr
 652 26 0.4696 0.4583 0.0399 0.0372 3
PLX-4720 SKMEL28 1.0000
uM
 72
hr
 694 22 0.5041 0.4583 0.0317 0.0372 4
PLX-4720 SKMEL28 3.1600
uM
 24
hr
 1
PLX-4720 SKMEL28 3.1600
uM
 24
hr
 2
PLX-4720 SKMEL28 3.1600
uM
 24
hr
 3
PLX-4720 SKMEL28 3.1600
uM
 24
hr
 4
PLX-4720 SKMEL28 3.1600
uM
 48
hr
 1012 47 0.5748 0.6099 0.0464 0.0568 1
PLX-4720 SKMEL28 3.1600
uM
 48
hr
 1117 74 0.6212 0.6099 0.0662 0.0568 2
PLX-4720 SKMEL28 3.1600
uM
 48
hr
 1144 71 0.6391 0.6099 0.0621 0.0568 3
PLX-4720 SKMEL28 3.1600
uM
 48
hr
 1071 56 0.6045 0.6099 0.0523 0.0568 4