Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 SKMEL28 0.0316
uM
 48
hr
 2366 87 1.3574 1.4792 0.0368 0.0349 3
PLX-4720 SKMEL28 0.0316
uM
 48
hr
 2276 76 1.3103 1.4792 0.0334 0.0349 4
PLX-4720 SKMEL28 0.0316
uM
 72
hr
 1246 45 0.9009 0.9677 0.0361 0.0321 1
PLX-4720 SKMEL28 0.0316
uM
 72
hr
 1299 50 0.9369 0.9677 0.0385 0.0321 2
PLX-4720 SKMEL28 0.0316
uM
 72
hr
 1285 34 0.9384 0.9677 0.0265 0.0321 3
PLX-4720 SKMEL28 0.0316
uM
 72
hr
 1500 41 1.0944 0.9677 0.0273 0.0321 4
PLX-4720 SKMEL28 0.1000
uM
 24
hr
 1
PLX-4720 SKMEL28 0.1000
uM
 24
hr
 2
PLX-4720 SKMEL28 0.1000
uM
 24
hr
 3
PLX-4720 SKMEL28 0.1000
uM
 24
hr
 4
PLX-4720 SKMEL28 0.1000
uM
 48
hr
 2646 95 1.5194 1.4169 0.0359 0.0350 1
PLX-4720 SKMEL28 0.1000
uM
 48
hr
 2792 100 1.6034 1.4169 0.0358 0.0350 2
PLX-4720 SKMEL28 0.1000
uM
 48
hr
 2252 72 1.2984 1.4169 0.0320 0.0350 3
PLX-4720 SKMEL28 0.1000
uM
 48
hr
 2172 79 1.2466 1.4169 0.0364 0.0350 4
PLX-4720 SKMEL28 0.1000
uM
 72
hr
 1113 32 0.8109 0.8664 0.0288 0.0301 1
PLX-4720 SKMEL28 0.1000
uM
 72
hr
 1190 37 0.8649 0.8664 0.0311 0.0301 2
PLX-4720 SKMEL28 0.1000
uM
 72
hr
 1152 37 0.8364 0.8664 0.0321 0.0301 3
PLX-4720 SKMEL28 0.1000
uM
 72
hr
 1308 37 0.9534 0.8664 0.0283 0.0301 4
PLX-4720 SKMEL28 0.3160
uM
 24
hr
 1
PLX-4720 SKMEL28 0.3160
uM
 24
hr
 2
PLX-4720 SKMEL28 0.3160
uM
 24
hr
 3
PLX-4720 SKMEL28 0.3160
uM
 24
hr
 4
PLX-4720 SKMEL28 0.3160
uM
 48
hr
 1993 86 1.1358 1.1229 0.0432 0.0365 1
PLX-4720 SKMEL28 0.3160
uM
 48
hr
 2269 79 1.3044 1.1229 0.0348 0.0365 2
PLX-4720 SKMEL28 0.3160
uM
 48
hr
 1758 57 1.0131 1.1229 0.0324 0.0365 3