Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
SB590885 K2 1.0000
uM
 72
hr
 1
SB590885 K2 1.0000
uM
 72
hr
 2
SB590885 K2 1.0000
uM
 72
hr
 3
SB590885 K2 1.0000
uM
 72
hr
 4
SB590885 K2 3.1600
uM
 24
hr
 1753 46 1.0039 0.6797 0.0262 0.0372 1
SB590885 K2 3.1600
uM
 24
hr
 1691 45 0.9681 0.6797 0.0266 0.0372 2
SB590885 K2 3.1600
uM
 24
hr
 669 35 0.3729 0.6797 0.0523 0.0372 3
SB590885 K2 3.1600
uM
 24
hr
 665 29 0.3741 0.6797 0.0436 0.0372 4
SB590885 K2 3.1600
uM
 48
hr
 2701 165 0.9255 0.5867 0.0611 0.0801 1
SB590885 K2 3.1600
uM
 48
hr
 2489 158 0.8507 0.5867 0.0635 0.0801 2
SB590885 K2 3.1600
uM
 48
hr
 912 100 0.2963 0.5867 0.1097 0.0801 3
SB590885 K2 3.1600
uM
 48
hr
 822 71 0.2741 0.5867 0.0864 0.0801 4
SB590885 K2 3.1600
uM
 72
hr
 1
SB590885 K2 3.1600
uM
 72
hr
 2
SB590885 K2 3.1600
uM
 72
hr
 3
SB590885 K2 3.1600
uM
 72
hr
 4
PLX-4720 K2 0.0032
uM
 24
hr
 3174 8 1.8620 1.6766 0.0025 0.0050 1
PLX-4720 K2 0.0032
uM
 24
hr
 2771 9 1.6244 1.6766 0.0032 0.0050 2
PLX-4720 K2 0.0032
uM
 24
hr
 2959 25 1.7256 1.6766 0.0084 0.0050 3
PLX-4720 K2 0.0032
uM
 24
hr
 2556 15 1.4944 1.6766 0.0059 0.0050 4
PLX-4720 K2 0.0032
uM
 48
hr
 3865 1 1.4101 1.3444 0.0003 0.0024 1
PLX-4720 K2 0.0032
uM
 48
hr
 3223 7 1.1737 1.3444 0.0022 0.0024 2
PLX-4720 K2 0.0032
uM
 48
hr
 4064 15 1.4777 1.3444 0.0037 0.0024 3
PLX-4720 K2 0.0032
uM
 48
hr
 3619 12 1.3163 1.3444 0.0033 0.0024 4
PLX-4720 K2 0.0032
uM
 72
hr
 1