Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | MZ7-mel | 0.0100 | uM | 24 | hr | 1491 | 14 | 1.1189 | 1.0212 | 0.0094 | 0.0082 | 2 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 24 | hr | 1137 | 7 | 0.8561 | 1.0212 | 0.0062 | 0.0082 | 3 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 24 | hr | 1312 | 6 | 0.9894 | 1.0212 | 0.0046 | 0.0082 | 4 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 48 | hr | 2773 | 36 | 0.8474 | 0.9895 | 0.0130 | 0.0193 | 1 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 48 | hr | 2903 | 52 | 0.8827 | 0.9895 | 0.0179 | 0.0193 | 2 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 48 | hr | 3712 | 79 | 1.1248 | 0.9895 | 0.0213 | 0.0193 | 3 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 48 | hr | 3655 | 91 | 1.1034 | 0.9895 | 0.0249 | 0.0193 | 4 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 72 | hr | 3020 | 41 | 1.2409 | 1.1567 | 0.0136 | 0.0171 | 1 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 72 | hr | 3212 | 41 | 1.3209 | 1.1567 | 0.0128 | 0.0171 | 2 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 72 | hr | 2813 | 53 | 1.1497 | 1.1567 | 0.0188 | 0.0171 | 3 |
| PLX-4720 | MZ7-mel | 0.0100 | uM | 72 | hr | 2249 | 52 | 0.9152 | 1.1567 | 0.0231 | 0.0171 | 4 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 24 | hr | 1677 | 19 | 1.2561 | 1.1367 | 0.0113 | 0.0100 | 1 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 24 | hr | 1662 | 5 | 1.2553 | 1.1367 | 0.0030 | 0.0100 | 2 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 24 | hr | 1363 | 17 | 1.0197 | 1.1367 | 0.0125 | 0.0100 | 3 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 24 | hr | 1359 | 18 | 1.0159 | 1.1367 | 0.0132 | 0.0100 | 4 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 48 | hr | 3849 | 36 | 1.1805 | 1.0185 | 0.0094 | 0.0130 | 1 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 48 | hr | 3057 | 21 | 0.9399 | 1.0185 | 0.0069 | 0.0130 | 2 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 48 | hr | 3070 | 47 | 0.9359 | 1.0185 | 0.0153 | 0.0130 | 3 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 48 | hr | 3355 | 68 | 1.0176 | 1.0185 | 0.0203 | 0.0130 | 4 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 72 | hr | 2971 | 41 | 1.2205 | 1.0713 | 0.0138 | 0.0142 | 1 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 72 | hr | 2318 | 24 | 0.9556 | 1.0713 | 0.0104 | 0.0142 | 2 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 72 | hr | 2934 | 52 | 1.2005 | 1.0713 | 0.0177 | 0.0142 | 3 |
| PLX-4720 | MZ7-mel | 0.0316 | uM | 72 | hr | 2214 | 33 | 0.9085 | 1.0713 | 0.0149 | 0.0142 | 4 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 24 | hr | 1717 | 6 | 1.2962 | 1.1936 | 0.0035 | 0.0050 | 1 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 24 | hr | 1607 | 4 | 1.2144 | 1.1936 | 0.0025 | 0.0050 | 2 |