Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | MMAC-SF | 1.0000 | uM | 48 | hr | 3001 | 163 | 0.7482 | 0.7644 | 0.0543 | 0.0555 | 4 |
| PLX-4720 | MMAC-SF | 1.0000 | uM | 72 | hr | 1379 | 295 | 0.3154 | 0.3362 | 0.2139 | 0.2176 | 1 |
| PLX-4720 | MMAC-SF | 1.0000 | uM | 72 | hr | 1528 | 365 | 0.3383 | 0.3362 | 0.2389 | 0.2176 | 2 |
| PLX-4720 | MMAC-SF | 1.0000 | uM | 72 | hr | 1505 | 316 | 0.3459 | 0.3362 | 0.2100 | 0.2176 | 3 |
| PLX-4720 | MMAC-SF | 1.0000 | uM | 72 | hr | 1497 | 311 | 0.3450 | 0.3362 | 0.2078 | 0.2176 | 4 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 24 | hr | 1 | ||||||
| PLX-4720 | MMAC-SF | 3.1600 | uM | 24 | hr | 2 | ||||||
| PLX-4720 | MMAC-SF | 3.1600 | uM | 24 | hr | 2912 | 113 | 1.0882 | 1.0625 | 0.0388 | 0.0464 | 3 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 24 | hr | 2819 | 152 | 1.0369 | 1.0625 | 0.0539 | 0.0464 | 4 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 48 | hr | 2851 | 237 | 0.6891 | 0.6791 | 0.0831 | 0.0933 | 1 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 48 | hr | 3075 | 249 | 0.7450 | 0.6791 | 0.0810 | 0.0933 | 2 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 48 | hr | 2610 | 272 | 0.6164 | 0.6791 | 0.1042 | 0.0933 | 3 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 48 | hr | 2822 | 296 | 0.6659 | 0.6791 | 0.1049 | 0.0933 | 4 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 72 | hr | 1101 | 573 | 0.1536 | 0.1456 | 0.5204 | 0.5336 | 1 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 72 | hr | 1019 | 565 | 0.1321 | 0.1456 | 0.5545 | 0.5336 | 2 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 72 | hr | 1067 | 568 | 0.1452 | 0.1456 | 0.5323 | 0.5336 | 3 |
| PLX-4720 | MMAC-SF | 3.1600 | uM | 72 | hr | 1102 | 581 | 0.1516 | 0.1456 | 0.5272 | 0.5336 | 4 |
| AZ-628 | MMAC-SF | 0.0032 | uM | 24 | hr | 1 | ||||||
| AZ-628 | MMAC-SF | 0.0032 | uM | 24 | hr | 2 | ||||||
| AZ-628 | MMAC-SF | 0.0032 | uM | 24 | hr | 2830 | 113 | 1.0563 | 1.0594 | 0.0399 | 0.0452 | 3 |
| AZ-628 | MMAC-SF | 0.0032 | uM | 24 | hr | 2878 | 145 | 1.0625 | 1.0594 | 0.0504 | 0.0452 | 4 |
| AZ-628 | MMAC-SF | 0.0032 | uM | 48 | hr | 3305 | 167 | 0.8273 | 0.9380 | 0.0505 | 0.0483 | 1 |
| AZ-628 | MMAC-SF | 0.0032 | uM | 48 | hr | 3752 | 167 | 0.9451 | 0.9380 | 0.0445 | 0.0483 | 2 |
| AZ-628 | MMAC-SF | 0.0032 | uM | 48 | hr | 3918 | 184 | 0.9844 | 0.9380 | 0.0470 | 0.0483 | 3 |
| AZ-628 | MMAC-SF | 0.0032 | uM | 48 | hr | 3980 | 204 | 0.9954 | 0.9380 | 0.0513 | 0.0483 | 4 |