Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | WM1552C | 0.0032 | uM | 24 | hr | 2699 | 161 | 1.0130 | 1.0243 | 0.0597 | 0.0609 | 1 |
| PLX-4720 | WM1552C | 0.0032 | uM | 24 | hr | 2767 | 172 | 1.0357 | 1.0243 | 0.0622 | 0.0609 | 2 |
| PLX-4720 | WM1552C | 0.0032 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | WM1552C | 0.0032 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | WM1552C | 0.0032 | uM | 48 | hr | 3160 | 184 | 0.9467 | 0.9756 | 0.0582 | 0.0618 | 1 |
| PLX-4720 | WM1552C | 0.0032 | uM | 48 | hr | 3501 | 166 | 1.0609 | 0.9756 | 0.0474 | 0.0618 | 2 |
| PLX-4720 | WM1552C | 0.0032 | uM | 48 | hr | 3344 | 256 | 0.9823 | 0.9756 | 0.0766 | 0.0618 | 3 |
| PLX-4720 | WM1552C | 0.0032 | uM | 48 | hr | 3069 | 200 | 0.9126 | 0.9756 | 0.0652 | 0.0618 | 4 |
| PLX-4720 | WM1552C | 0.0032 | uM | 72 | hr | 6461 | 478 | 1.1605 | 1.0391 | 0.0740 | 0.0768 | 1 |
| PLX-4720 | WM1552C | 0.0032 | uM | 72 | hr | 5995 | 406 | 1.0841 | 1.0391 | 0.0677 | 0.0768 | 2 |
| PLX-4720 | WM1552C | 0.0032 | uM | 72 | hr | 5134 | 430 | 0.9124 | 1.0391 | 0.0838 | 0.0768 | 3 |
| PLX-4720 | WM1552C | 0.0032 | uM | 72 | hr | 5611 | 459 | 0.9993 | 1.0391 | 0.0818 | 0.0768 | 4 |
| PLX-4720 | WM1552C | 0.0100 | uM | 24 | hr | 2719 | 154 | 1.0237 | 1.0451 | 0.0566 | 0.0582 | 1 |
| PLX-4720 | WM1552C | 0.0100 | uM | 24 | hr | 2842 | 170 | 1.0664 | 1.0451 | 0.0598 | 0.0582 | 2 |
| PLX-4720 | WM1552C | 0.0100 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | WM1552C | 0.0100 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | WM1552C | 0.0100 | uM | 48 | hr | 3536 | 205 | 1.0596 | 0.9938 | 0.0580 | 0.0656 | 1 |
| PLX-4720 | WM1552C | 0.0100 | uM | 48 | hr | 3233 | 192 | 0.9673 | 0.9938 | 0.0594 | 0.0656 | 2 |
| PLX-4720 | WM1552C | 0.0100 | uM | 48 | hr | 3383 | 246 | 0.9979 | 0.9938 | 0.0727 | 0.0656 | 3 |
| PLX-4720 | WM1552C | 0.0100 | uM | 48 | hr | 3220 | 233 | 0.9502 | 0.9938 | 0.0724 | 0.0656 | 4 |
| PLX-4720 | WM1552C | 0.0100 | uM | 72 | hr | 6883 | 495 | 1.2390 | 1.1289 | 0.0719 | 0.0708 | 1 |
| PLX-4720 | WM1552C | 0.0100 | uM | 72 | hr | 6774 | 420 | 1.2324 | 1.1289 | 0.0620 | 0.0708 | 2 |
| PLX-4720 | WM1552C | 0.0100 | uM | 72 | hr | 5939 | 457 | 1.0633 | 1.1289 | 0.0769 | 0.0708 | 3 |
| PLX-4720 | WM1552C | 0.0100 | uM | 72 | hr | 5452 | 395 | 0.9809 | 1.1289 | 0.0725 | 0.0708 | 4 |
| PLX-4720 | WM1552C | 0.0316 | uM | 24 | hr | 2704 | 124 | 1.0297 | 1.0309 | 0.0459 | 0.0522 | 1 |