Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | WM-115 | 3.1600 | uM | 48 | hr | 406 | 51 | 0.7167 | 0.7919 | 0.1256 | 0.1219 | 4 |
| PLX-4720 | WM-115 | 3.1600 | uM | 72 | hr | 1434 | 560 | 0.2883 | 0.3017 | 0.3905 | 0.3812 | 1 |
| PLX-4720 | WM-115 | 3.1600 | uM | 72 | hr | 1393 | 526 | 0.2860 | 0.3017 | 0.3776 | 0.3812 | 2 |
| PLX-4720 | WM-115 | 3.1600 | uM | 72 | hr | 1548 | 598 | 0.3134 | 0.3017 | 0.3863 | 0.3812 | 3 |
| PLX-4720 | WM-115 | 3.1600 | uM | 72 | hr | 1536 | 569 | 0.3190 | 0.3017 | 0.3704 | 0.3812 | 4 |
| AZ-628 | WM-115 | 0.0032 | uM | 24 | hr | 607 | 21 | 1.1192 | 1.1922 | 0.0346 | 0.0464 | 1 |
| AZ-628 | WM-115 | 0.0032 | uM | 24 | hr | 712 | 35 | 1.2930 | 1.1922 | 0.0492 | 0.0464 | 2 |
| AZ-628 | WM-115 | 0.0032 | uM | 24 | hr | 582 | 35 | 1.0447 | 1.1922 | 0.0601 | 0.0464 | 3 |
| AZ-628 | WM-115 | 0.0032 | uM | 24 | hr | 717 | 30 | 1.3121 | 1.1922 | 0.0418 | 0.0464 | 4 |
| AZ-628 | WM-115 | 0.0032 | uM | 48 | hr | 820 | 22 | 1.6111 | 1.0559 | 0.0268 | 0.0302 | 1 |
| AZ-628 | WM-115 | 0.0032 | uM | 48 | hr | 2 | ||||||
| AZ-628 | WM-115 | 0.0032 | uM | 48 | hr | 356 | 9 | 0.7006 | 1.0559 | 0.0253 | 0.0302 | 3 |
| AZ-628 | WM-115 | 0.0032 | uM | 48 | hr | 441 | 17 | 0.8560 | 1.0559 | 0.0385 | 0.0302 | 4 |
| AZ-628 | WM-115 | 0.0032 | uM | 72 | hr | 3239 | 86 | 1.0401 | 1.0291 | 0.0266 | 0.0295 | 1 |
| AZ-628 | WM-115 | 0.0032 | uM | 72 | hr | 2939 | 84 | 0.9418 | 1.0291 | 0.0286 | 0.0295 | 2 |
| AZ-628 | WM-115 | 0.0032 | uM | 72 | hr | 3355 | 94 | 1.0757 | 1.0291 | 0.0280 | 0.0295 | 3 |
| AZ-628 | WM-115 | 0.0032 | uM | 72 | hr | 3326 | 116 | 1.0589 | 1.0291 | 0.0349 | 0.0295 | 4 |
| AZ-628 | WM-115 | 0.0100 | uM | 24 | hr | 665 | 33 | 1.2070 | 1.4692 | 0.0496 | 0.0415 | 1 |
| AZ-628 | WM-115 | 0.0100 | uM | 24 | hr | 631 | 22 | 1.1631 | 1.4692 | 0.0349 | 0.0415 | 2 |
| AZ-628 | WM-115 | 0.0100 | uM | 24 | hr | 951 | 39 | 1.7418 | 1.4692 | 0.0410 | 0.0415 | 3 |
| AZ-628 | WM-115 | 0.0100 | uM | 24 | hr | 963 | 39 | 1.7647 | 1.4692 | 0.0405 | 0.0415 | 4 |
| AZ-628 | WM-115 | 0.0100 | uM | 48 | hr | 890 | 43 | 1.7100 | 1.1906 | 0.0483 | 0.0498 | 1 |
| AZ-628 | WM-115 | 0.0100 | uM | 48 | hr | 685 | 21 | 1.3405 | 1.1906 | 0.0307 | 0.0498 | 2 |
| AZ-628 | WM-115 | 0.0100 | uM | 48 | hr | 419 | 27 | 0.7914 | 1.1906 | 0.0644 | 0.0498 | 3 |
| AZ-628 | WM-115 | 0.0100 | uM | 48 | hr | 483 | 27 | 0.9206 | 1.1906 | 0.0559 | 0.0498 | 4 |